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KOLOT – The Fog of War - Jewish Ledger

Jewish Ledger
KOLOT – The Fog of War
By Anat and Etan Markus
Anat and Etan Markus were born and raised in Israel, but they have lived in Connecticut for 30 years first in Manchester, then in West Hartford and now in Mansfield, a short distance from the University of Connecticut’s Storrs campus where Etan is a professor and researcher
All three Markus children are American born, graduates of what was then the Bess and Paul Sigel Hebrew Academy in Bloomfield and Hall High School in West Hartford. In recent years they each made aliyah Dror, 31, lives in the Tel Aviv area and is in the process of getting his doctorate in Big Data polling at Hebrew University; Hadar, 30, lives in Tel Aviv with her husband, Netanel, and their one-year-old son; and Talya, 28, a student at ....

West Hartford , United States , Mohafazat Baalbek Hermel , Israel General , Tel Aviv , Hall High School , Hebrew University , Ha Afon , Afula Hartford , Etan Markus , Menachem Hadar , Hadassah Medical School , Akko Hotel Efendi , Paul Sigel Hebrew Academy In Bloomfield , Magav Border Police , University Of Connecticut Storrs , Paul Sigel Hebrew Academy , Big Data , Political Science , Hotel Efendi , Uri Bruri , Border Police , Mass Turnpike , மேற்கு ஹார்ட்ஃபோர்ட் , ஒன்றுபட்டது மாநிலங்களில் , இஸ்ரேல் ஜநரல் ,

Surrogacy & IVF: Timeline Start to Finish for Intended Parents in Israel

Surrogacy & IVF: Timeline Start to Finish for Intended Parents in Israel
themedialine.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from themedialine.org Daily Mail and Mail on Sunday newspapers.

New Haven , United States , Yale University , Brett Griffin Young , Scott Buckley , Department Of Obstetrics , Client Services , Hadassah Medical School At Hebrew University , Head Of International Client Services , England Fertility Institute , Yale University School Of Medicine , Boston College Law School , Boston College , Eastern Daylight Time , New England Fertility Institute , Circle Surrogacy , Egg Donation , Trusted Mideast News , Mideast Daily News , Media Line , Medical Director , New England Fertility , Hadassah Medical School , Hebrew University , Yale University School , Vice President ,

Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling

Science for just $15 USD.
Abstract
Obesity is a global epidemic causing morbidity and impaired quality of life. The melanocortin receptor 4 (MC4R) is at the crux of appetite, energy homeostasis, and body-weight control in the central nervous system and is a prime target for anti-obesity drugs. Here, we present the cryo-EM structure of the human MC4R-G
s signaling complex bound to the agonist setmelanotide, a cyclic peptide recently approved for the treatment of obesity. The work reveals the mechanism of MC4R activation, highlighting a molecular switch that initiates satiation signaling. In addition, our findings indicate that Ca
2+ is required for agonist but not antagonist efficacy. These results fill a gap in understanding MC4R activation and could guide the design of future weight management drugs.View Full Text ....

Israel General , Hebrew University , Cancer Research , Institute For Medical Research Israel , Hadassah Medical School , Department Of Developmental Biology , Developmental Biology , Medical Research Israel Canada , இஸ்ரேல் ஜநரல் , ஹீப்ரு பல்கலைக்கழகம் , புற்றுநோய் ஆராய்ச்சி , ஹடாஸா மருத்துவ பள்ளி , துறை ஆஃப் வளர்ச்சி உயிரியல் , வளர்ச்சி உயிரியல் , மருத்துவ ஆராய்ச்சி இஸ்ரேல் கனடா ,

Scientists reach new milestone in vaccine development for leishmaniasis

E-Mail
Researchers have taken an important step forward in developing a controlled human infection model to test leishmaniasis vaccines.
The University of York-led study identified and characterised a new strain of Leishmania parasite that will form the basis of a new controlled human infection model for the disease which is transmitted by the bite of sand flies. The team then produced the parasite to the standards required for use in human clinical studies.
The use of controlled human infection models has already proved invaluable in accelerating vaccine development for cholera, malaria, typhoid, influenza and other important infectious diseases. Such models are also being developed as part of the fight against COVID-19. ....

Israel General , United States , Czech Republic , United Kingdom , Hebrew University , Vibalogics Gmb , Paul Kaye , Hull York Medical School , Nature Communications , Hadassah Medical School , United Kingdom Medical Research Council , Department For International Development , Department Of Microbiology , Tropical Diseases At Tel Aviv University , University Of York , Mcgill University , Department Of Parasitology At Charles University , South America , South Asia , Middle East , East Africa , Charles University , Geographic Medicine , Tropical Diseases , Tel Aviv University , Vibalogics Gmbh ,

Best of Last Year: The top MedicalXpress articles of 2020

Best of Last Year: The top MedicalXpress articles of 2020
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

United Kingdom , New South Wales , Sankt Peterburg , Stanford University , United States , University Of California San Francisco , University Of California San Diego , San Francisco , Anna Aksenova , Amesh Adalja , Frank Esper , William Bryan , Johnjoe Mcfadden , Amy Goss , University Of California , Hadassah Medical School , Cleveland Clinic Children Center , National Health , Philipps University Marburg , University Of Surrey , Weizmann Institute Of Science , University Of Arizona Health Sciences , Stanford University School Of Medicine , Centre For Healthy Brain , University Of Michigan , University Of British Columbia Okanagan ,