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Immune dysregulation can affect the efficacy of CAR T therapy in some lymphoma patients

Immune dysregulation can affect the efficacy of CAR T therapy in some lymphoma patients
Chimeric antigen receptor T-cell therapy, or CAR T, has been a breakthrough in the treatment of blood cancers such as acute lymphoblastic leukemia and diffuse large B-cell lymphoma. Clinical studies have shown overall response rates of more than 80% with an ongoing response of nearly 40% more than two years after therapy. However, the cellular immunotherapy doesn t work for every patient.
Moffitt Cancer Center, one of the leading centers for cellular immunotherapy, is researching why some patients have a better CAR T response than others and what can be done to improve the treatment s effectiveness. In a new study published in ....

United States , Frederick Locke , Michael Jain , Emily Henderson , American Society Of Hematology , Cellular Immunotherapy Department At Moffitt , Oncology Program , Cellular Immunotherapy Department , Moffitt Cancer Center , Cancer Center , American Society , Vice Chair , Marrow Transplant , Immuno Oncology Program , Moffitt Cancer , Acute Lymphoblastic Leukemia , Chimeric Antigen Receptor , Hodgkin Lymphoma , Non Hodgkin Lymphoma , T Cell , ஒன்றுபட்டது மாநிலங்களில் , ஃப்ரெடரிக் பூட்டு , மைக்கேல் ஜெயின் , எமிலி ஹென்டர்சன் , அமெரிக்கன் சமூகம் ஆஃப் ஹீமாட்டாலஜி , செல்லுலார் நோயெதிர்ப்பு சிகிச்சை துறை இல் மாஃபிட் ,

Takeda Achieves Industry-Leading Positions in 2021 Access to Medicine Index

Takeda Achieves Industry-Leading Positions in 2021 Access to Medicine Index
Wednesday, January 27, 2021 11:40AM IST (6:10AM GMT)

Company Ranked Sixth Overall and Leads the Pharmaceutical Industry in Governance of Access
Secured Industry-Leading Positions in All Three Technical Areas Evaluated
Shows Strong Performance in Health System Strengthening and Compliance

(TSE:4502/NYSE:TAK) (“Takeda”) has earned an industry-leading position within the 2021
Access to Medicine (AtM) Index published today. Specifically the company achieved notable, high scores in all three technical areas evaluated by the Index, including being ranked first in Governance of Access. Takeda also demonstrated strong performance in the areas of health system strengthening, compliance and R&D capacity building, according to the Index. ....

United States , United Kingdom , Christophe Weber , Kazumi Kobayashi , Ricardo Marek , Susanne Weissbaecker , Company Ranked Sixth Overall , Takeda Pharmaceutical Company Limited , Melinda Gates Foundation , Research Development , Takeda Pharmaceutical Company , Shows Strong Performance In Health System , Access To Medicine Foundation , Ranked Sixth Overall , Pharmaceutical Industry , Industry Leading Positions , All Three Technical Areas , Strong Performance , Health System Strengthening , Pharmaceutical Company Limited , Atm Index , Medicine Index , Emerging Markets Business Unit , Access First , Emerging Markets Region , Innovative Healthcare Access ,

F. Hoffmann-La Roche Ltd: Roche renews partnership with Sysmex to deliver haematology testing solutions

F. Hoffmann-La Roche Ltd: Roche renews partnership with Sysmex to deliver haematology testing solutions
This successful long-running partnership continues to evolve and bring haematology testing innovations to laboratories, globally
The new agreement aims to utilise the IT systems to lead to improved clinical decision making and customer experience
Blood disorders have a high impact, not only for patients but for society as a whole, accounting for a third of all central laboratory tests
1
Basel, 25 January 2021 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that, on 14 December, 2020, it signed a Global Business Partnership Agreement (GBP) with Sysmex. Under this new framework, the parties renewed their commitment to the long standing Distribution, Sales and Service (DSS) agreement, allowing Roche to continue to distribute Sysmex haematology products, including instruments and reagents. ....

United States , South Africa , New Zealand , Nathalie Meetz , Jon Kaspar Bayard , Daniel Grotzky , Karl Mahler , Sabine Borngr , Gerard Tobin , Bruno Eschli , Birgit Masjost , Loren Kalm , Lisa Tuomi , Thomas Schinecker , Patrick Barth , Karsten Kleine , Laboratory Solutions , Overview Of The Global Business Partnership Agreement , Service Agreement , It Solutions Collaboration Agreement , Roche Group , Pharmaceuticals Industry , Roche Group Media Relations , Global Business Partnership Agreement , Global Business Partnership , Distributorship Sales ,

Genomic test has lower prognostic accuracy in minority patients with breast cancer

Genomic test has lower prognostic accuracy in minority patients with breast cancer
Black women have higher recurrence and mortality rates than non-Hispanic white women for certain types of breast cancer, according to a University of Illinois Chicago researcher s study published recently in
JAMA Oncology.
Dr. Kent Hoskins, associate professor in the UIC College of Medicine s division of hematology/oncology, and co-leader of the Breast Cancer Research group in the University of Illinois Cancer Center, published the study, Association of race/ethnicity and the 21-gene Recurrence Score with breast cancer-specific mortality among US women in the Jan. 21 online issue.
Hoskins and the research team sought to discover if breast cancer-specific mortality among women with estrogen receptor-positive, axillary node-negative breast cancer differs by race within risk categories defined by the Oncotype Recurrence Score, or RS, which is a genomic test that analyzes the activity ....

United States , University Of Illinois , Kent Hoskins , Emily Henderson , Breast Cancer Research , Ui Cancer Center , University Of Illinois Chicago , College Of Medicine , University Of Illinois Cancer Center , Illinois Chicago , Illinois Cancer Center , Recurrence Score , Oncotype Recurrence Score , African American , Associate Professor , Breast Cancer , ஒன்றுபட்டது மாநிலங்களில் , பல்கலைக்கழகம் ஆஃப் இல்லினாய்ஸ் , கேண்ட் ஹோஸ்கின்ஸ் , எமிலி ஹென்டர்சன் , மார்பக புற்றுநோய் ஆராய்ச்சி , உய் புற்றுநோய் மையம் , பல்கலைக்கழகம் ஆஃப் இல்லினாய்ஸ் சிகாகோ , கல்லூரி ஆஃப் மருந்து , பல்கலைக்கழகம் ஆஃப் இல்லினாய்ஸ் புற்றுநோய் மையம் , இல்லினாய்ஸ் சிகாகோ ,

Cancer patients have higher risk of severe COVID -19 infection than non-cancer patients

Cancer patients have higher risk of severe COVID -19 infection than non-cancer patients
Patients with inactive cancer and not currently undergoing treatments also face a significantly higher risk of severe illness from COVID-19, a new study from Penn Medicine published online today in
JNCI Cancer Spectrum shows.
Past reports have established an increased risk of severe disease and death for sick or hospitalized cancer patients with COVID-19 compared to patients without cancer, but less is known about patients in the general population.
The findings underscore the importance of COVID-19 mitigation, like social distancing and mask-wearing, and vaccinations for all patients, not just those recently diagnosed or with active disease. ....

Karan Maxwell , Emily Henderson , Member Of The Abramson Cancer Center , University Of Pennsylvania , Basser Center , Perelman School Of Medicine , Abramson Cancer Center , Penn Medicine , Perelman School , Penn Medicine Biobank , Study Senior Author , Assistant Professor , Health Care , கரண் மேக்ஸ்வெல் , எமிலி ஹென்டர்சன் , உறுப்பினர் ஆஃப் தி புற்றுநோய் மையம் , பல்கலைக்கழகம் ஆஃப் பென்சில்வேனியா , பாஸர் மையம் , பெரல்மேன் பள்ளி ஆஃப் மருந்து , பென் மருந்து , பெரல்மேன் பள்ளி , படிப்பு மூத்தவர் நூலாசிரியர் , உதவியாளர் ப்ரொஃபெஸர் , ஆரோக்கியம் பராமரிப்பு ,