Page 37 - Cell Stem News Today

Date Time Brain organoids uncover mechanisms of virus-induced microcephaly Human brain organoids stained for neural stem cells (magenta) and Zika virus (left, green) och Herpes Simplex Virus 1 (right, green). Credits: Krenn/CellStemCell/IMBA A study involving researchers at Karolinska Institutet and IMBA – Institute of Molecular Biotechnology of the Austrian Academy of Sciences – demonstrates how zika and herpes viruses can lead to brain malformations during early pregnancy. The researchers...

Kyoto University Naïve and primed PSCs (iPS cells and embryonic stem cells) represent different periods in development (before and after the embryo implants itself into the uterus). Naïve PSCs can become all the major cell components that make up the villi, which goes on to become the placenta. Primed PSCs cannot and instead form cells that lead to the amnion. The Yasuhiro Takashima lab shows that naïve iPS cells can be induced to form all the stages that mimic early placenta dev...

3D Lab Model Developed in Search for New Therapies for AMD Source: Clark and Company/Getty Images April 1, 2021 Share Age-related macular degeneration (AMD), which leads to a loss of central vision, is the most frequent cause of blindness in adults 50 years of age or older, affecting an estimated 196 million people worldwide. There is no cure, though treatment can slow the onset and preserve some vision. Researchers at the University of Rochester report that they have made an important breakth...

Scientists grow human tear glands in a lab and actually make them cry Dutch researchers have an ambitious vision for their organoid. Listen - 02:47 Getty Images Disembodied human tear glands that cry sound like something out of a sci-fi movie. But in the Netherlands, functional tear glands that dont attach to anyones eyes (or emotions) are starring in their own real-life drama.  Researchers from the Hu...

Hubrecht Institute and UMC Utrecht researchers presented lab-grown tear glands using stem cells, simulating the actual ones. In a CΙNET report, disembodied human tear glands that cry sound is described like something inspired by a sci-fi movie. However, in the Netherlands, functional tear glands not attached to any individuals eyes or even emotions, are said to be stirring in their own real-life drama. Essentially, the researchers are hoping these so-called organoids can function as models for...

Tear glands cry in a dish Human stem-cell derived organoids make tears. A confocal image of a mouse lacrimal-gland organoid with the tear product Lcn2 labelled in red, showing that the organoids make tears. Credit: Yorick Post, Hubrecht Institute A team of researchers, led by Marie Bannier-Hélaouët of the Hubrecht Institute in the Netherlands, has developed organoids that swell up with tears in a petri dish, modelled on tear glands. This video shows a human organoid, based on tear glands, swe...

Scientists grow human tear glands in a lab and actually make them cry CNET 4 days ago © Provided by CNET Getty Images Disembodied human tear glands that cry sound like something out of a sci-fi movie. But in the Netherlands, functional tear glands that dont attach to anyones eyes (or emotions) are starring in their own real-life drama.  Researchers from the Hubrecht Institute and UMC Utrecht used stem cells to grow tiny tear glands in a petri dish that mimic the real thing. They hope thes...

Creation of mini-organs using stem cells will help research into tear-related disorders

Credit: Marie Bannier-Hélaouët, copyright Hubrecht Institute Researchers from the lab of Hans Clevers (Hubrecht Institute) and the UMC Utrecht used organoid technology to grow miniature human tear glands that actually cry. The organoids serve as a model to study how certain cells in the human tear gland produce tears or fail to do so. Scientists everywhere can use the model to identify new treatment options for patients with tear gland disorders, such as dry eye disease. Hopefully in the futu...

Scientists have grown miniature human tear glands capable of crying. Researchers say the organoids serve as a model to study how certain cells in the human tear gland produce tears or fail to do so. They hope it may become possible to transplant the lab-grown glands into patients with non-functioning tear glands. The tear gland is in the upper part of the eye socket, and secretes tear fluid which is essential for lubrication and nutrition of the cornea and has antibacterial components. Ophthalm...