usually trying to find a solution to a problem, and feel better. if your brain is genetically set up a certain way, it works. that's what you have to acknowledge in drug addicts. they use drugs because they work. they do feel better. a lot better. for an extended period of time many times. and then a second phenomenon kicks in. which is the disease of addiction. whereby, in spite of it no longer working or having serious consequences in their life, the what i like to call it the do it again part of their brain has been altered in such a way to require them to do it again, do it again. >> larry: why, dr. amen, does the addiction, the need for the cocaine do to the brain? because the brain still knows it's damaging. >> it damages it over time. >> larry: the brain is damaged. >> yes. and so the emotional part of the brain, the pleasure center in the brain hijacks it. and it's damaging your prefrontal cortex, so that over time, you have less and less and