S.F. on course for record-breaking number of drug overdoses in 2021 FacebookTwitterEmail 1of6 A reported 252 people died of drug overdoses in San Francisco from January to April of 2021.Nick Otto/Special to The Chronicle 2020Show MoreShow Less 2of6 Discarded syringes on a sidewalk in the Tenderloin.Nick Otto/Special to The Chronicle 2020Show MoreShow Less 3of6 Paramedics work to revive an overdose victim in the Tenderloin.Nick Otto/Special to The Chronicle 2020Show MoreShow Less 4of6 Many of the overdose deaths in the city occur in the Tenderloin.Nick Otto/Special to The Chronicle 2020Show MoreShow Less 5of6 A confiscated pipe used to smoke narcotics on the trunk of a car in the Tenderloin.Nick Otto/Special to The Chronicle 2020Show MoreShow Less