Science News | Scientists Turn Up Spotlight on Cells in Tiss

Get latest articles and stories on Science at LatestLY. A new advance overcomes present limitations in spatial transcriptomics with a DNA nanotechnology-driven method called 'Light-Seq.' Light-Seq allows researchers to 'geotag' the full repertoire of RNA sequences with unique DNA barcodes exclusive to a few cells of interest. These target cells are selected using light under a microscope via a fast and effective photocrosslinking process, and their RNAs made available to next-generation sequencing with the help of a new DNA nanotechnology-driven technique. This entire process can then be repeated for different cell populations in the same sample. Science News | Scientists Turn Up Spotlight on Cells in Tissues So RNA Could Explain Disease and Biology.

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