E-Mail IMAGE: Dr. Wylie, the director of the Rocco Ortenzio Neuroimaging Center at Kessler Foundation, conducts research in cognitive fatigue in healthy individuals and populations with multiple sclerosis, brain injury, and Gulf... view more Credit: Kessler Foundation/Jody Banks East Hanover, NJ. April 1, 2021. A team of New Jersey researchers has shown that changes in perceptual certainty and response bias, two central metrics of signal detection theory (SDT), correlate with changes in cognitive fatigue. They also show that SDT measures change as a function of changes in brain activation. This finding was reported in The authors are Glenn Wylie, DPhil, Brian Yao, PhD, and John DeLuca, PhD, of Kessler Foundation, and Joshua Sandry, PhD, of Montclair State University.