diagnosis when there's a mobile app to do the job — the future of artificial intelligence. and coming up in the sport on bbc news. as anthonyjoshua prepares for the biggest night of his life. he tells the bbc he's a "man of the people" and still the same as when he was 17. good evening and welcome to the bbc news at six. theresa may says she wants a mandate from every part of the uk when she goes into brexit negotiations. the prime minister was speaking in south wales, taking the tory campaign into what has traditionally been a labour heartland. and despite substantial leads for the tories in recent polls she warned party workers against being complacent. from bridgend, here's our political editor laura kuenssberg on a conservative party determined to turn the electoral map blue. if the tories want headlines about a new iron lady... they are not very su btle new iron lady... they are not very subtle about it. theresa may came to inspect this factory in newport. must be doing something right, she joked. she needs to to achieve a big if, to turn wales into tory territory. it is audacious to pop up in labourland at territory. it is audacious to pop up in labour land at the start. she was only with activists and friends, but her appeal is to you. give me a mandate to lead britain. give me a mandate to lead britain. give me a mandate to lead britain. give me a mandate to speak for britain. give mea mandate to speak for britain. give me a mandate to fight for britain and give me a mandate to deliverfor britain. she would not be drawn again on whether she will raise or lower taxes. how far are you willing to grow to grab seats in parts of the country, that until now have been a labour heartlands?|j the country, that until now have been a labour heartlands? i will be out and about in all sorts of areas, all part of the country, taking this message, vote for me and the local conservative candidate is a vote to strengthen our hand in the brexit negotiations. really? from coast to coast taking places like porthcawl would be taking a lifelong labour voters like this couple, who have almost decided to do it. would be the first time ever because the valleys is a labour stronghold.” the first time ever because the valleys is a labour stronghold. i am on the border, but i voted for out in the referendum. i don't know whether to vote labour or conservative this time. my father would spin in his grave. conservative this time. my father would spin in his gravel conservative this time. my father would spin in his grave. i am a typical labour voter, but whether i will be voting labour this year, because i have no confidence in jeremy corbyn. but then again i don't think i will be voting for conservative. i have put the same effort into the way i voted last time. i voted effort into the way i voted last time. ivoted labour last effort into the way i voted last time. i voted labour last time. what about father and son? he has been labour all his life. i think he has swung to theresa may now. definitely. jeremy corbyn, goodbye. here, labour is in charge in cardiff, but even their leader admitsjeremy cardiff, but even their leader admits jeremy corbyn has cardiff, but even their leader admitsjeremy corbyn has some way to go. to prove himself as a leader and to prove to be a candidate as prime minister. we have some weeks to go before the poll itself, but that is the challenge. even from the start of theircampaign, the challenge. even from the start of their campaign, plied cymru will not hesitate to stir up old memories. if people are considering conservative, remember the past. the tories have not been a friend to wales. we are not rolling over for any tory to take our seats, we will be out in force. it is early days, but any day out on the campaign trail is precious. leaders turn up two places where they think they are in the game. with possible gains in wales and scotland, theresa may is not just contemplating wales and scotland, theresa may is notjust contemplating a tory majority, but hoping to make true her claim, there are no torino go areas. brexit might have redraw the map, but she wants to colour it blue. yet, as she swept away, it won't be easy. here are anywhere else, the tories can be sure they will always be welcome. so theresa may says this election is about giving her a clear mandate for the tough brexit talks ahead. for labour, accused of sending confusing signals on brexit, today was a chance to clarify its position. the shadow brexit secretary sir keir starmer said labour accepted that free movement of people could not continue, but suggested eu nationals could still be allowed in if they had a guaranteed job offer. he also said labour would work harder to stay within the eu's customs union, which governs trade. and labour has pledged to unilaterally protect the legal rights of eu nationals already living in the uk. our deputy political editor john pienaar reports. this is where the election is being decided, not in political meetings, but on the streets, in the homes and in the heads of voters. we are choosing a pack for britain after brexit and on this nation dividing issue, labour is taking a gamble that will win some voters and maybe lose others. here in barking, a lot of places where people voted labour and then chose to leave the eu. today, labour is out to show it is more pro—europe, more open to compromise than theresa may's tories from the start. eu nationals here would keep their rights. on day one ofa would keep their rights. on day one of a labour government, we will immediately guarantee that all eu nationals currently living in the uk will see no change in their legal status as a result of brexit. day one, big commitment. after brexit, all rights of free movement across the uk border had to change, but then more clarity on labour policy. get a job offer, you are free to come in. freedom of movement will have to go, so therefore it has to change but we need immigration that works for the communities and the economy. that means there has to be movement of people to come and work in this country. how that is managed, will have to be resolved but the last thing we want is for businesses to go bankrupt. then he poured cold water on the dream to conquer markets beyond europe. poured cold water on the dream to conquer markets beyond europelj conquer markets beyond europe.” think it is worth keeping the customs union option on the table and see where we are in two years, but we have to focus on the eu trade agreement, because that is 44% of oui’ agreement, because that is 44% of our trade. not hypothetical free—trade deals elsewhere in the world 7 free—trade deals elsewhere in the world? the idea of hypothetical free—trade deals in 2019 compensating for losing the eu is something nobody is contemplating. until now, labour and the tories have been sounding more alike over brexit than either side would admit. now labour is showing more of its pro—european colours and the party needs to motivate its activists and loyal supporters. but around here and places like this, it is a gamble. for many people, this is a gut issue. there is enough people in this small island, otherwise it will be like a ship, we will sink. no need to let the europeans in to do thatjob? need to let the europeans in to do that job? no, no need to let the europeans in to do thatjob? no, no need. i agree. no british can get a job, all the foreigners and other people coming m, foreigners and other people coming in, they are taking them. labour says if you are european and you have a job, they are welcome. as long as they have a job to come to and it is documented and it is not just sort of, slipping in, then yes, 110 just sort of, slipping in, then yes, no problem with that. but now it is about which side can convince the voters. what do others make of labour policy? not much. this is the first time we have heard this clarity of free movement. u nfortu nately for this clarity of free movement. unfortunately for jeremy corbyn this clarity of free movement. unfortunately forjeremy corbyn and keir starmer, many on the labour front bench don't agree with them. he's trying to put a united front on a party which is split down the middle on this issue. it amounts to something too little, too late and model. i am still not clear whether the labour party believes we should be in or out of the single market. they say they don't agree with the government's negotiating strategy but they voted for it. labour has failed to sell a clear policy line, but now it is campaign time and get people to like what is on offer. assuming they can get the voters' attention. and you can find out more on where all the parties stand on the brexit negotiations on our website. that's at bbc.co.uk/news. the liberal democrat leader, tim farron, has said he does not think gay sex is a sin, having declined to answer the question on several occasions during the election campaign. in an interview with bbc news, mr farron, who's a christian, acknowledged that the matter had become an issue for him. mr farron was speaking to our political correspondent, eleanor garnier. i think it's fair to say i've answered the question. it's a subject he's been asked about again... you won't say whether you think having gay sex is a sin... and again... does the honourable member think that being gay is a sin? and again... you said, homosexuality is not a sin. they said that you didn't answer when they asked you whether gay sex was a sin. while he said being gay was fine, until today, the lib dem leader, a committed christian, has refused to answer this question. i don't believe gay sex is a sin. i take the view that, as a political leader, though, myjob is not to pontificate on theological matters. this had become a talking point, an issue. in that case, if people have kind of got the wrong opinion of what i think about these issues, then that's something it is right to correct. it's taken him almost two years, since becoming the leader of the lib dems, to clarify his position. but the pressure has increased since the election was called. so, what's changed in the last 48 hours that you are now able to say that you don't think gay sex is a sin, yet for the last two years you have very blatantly swerved the question? well, i'm quite careful how i talk about my faith. i'm not... i mean, i don't bang on about it. i don't make a secret out of it. so you were either misleading people before, or you are misleading people now. which is it? so the answer to that is that i was asked a question early on, and i didn't want to get into a sort of series of questions unpicking the theology of the bible. isn't itjust that it is your christian belief, and you didn't want to admit it? no, that's not the case. what i want is to make sure that we deal with something that's become an issue. so this is blatant electioneering? it's a sense of understanding that, you know, the questions was asked of me a week ago. i don't think people want a political party leaders telling them what is and isn't a sin. mr farron insisted the lib dems have undoubtedly the best record on gay rights out of all political parties. but it's clear the issue and the questions around it have troubled him personally, and politically, too. eleanor garnier, bbc news, westminster. the confectionary giant nestle is planning to cut up to 300 jobs and move production of the blue riband chocolate biscuit to poland. the proposed job losses will mainly affect the company's sites in york and newcastle. nestle, which employs 8,000 people in the uk, said it hoped to achieve the cuts through voluntary redundancies. president trump's daughter, ivanka, has defended his record on women's rights during a g20 summit in berlin. appearing alongside the german chancellor angela merkel, she said her father had always encouraged her and demonstrated his belief in the potential of women through his employment practices. from berlin, jenny hill sent this report. taking her place among the world's most powerful women. the first daughter, rubbing shoulders with a chancellor, a queen and a banker. though, almost immediately, ivanka trump found herself defending a president. he's been a tremendous champion of supporting families, and enabling them to thrive. donald trump's special adviser persisted. as a daughter, i can speak on a very personal level, knowing that he encouraged me and enabled me to thrive. i grew up in a house where there was no barriers to what i could accomplish. and the first daughter has gone on to make powerfulfriends. her first solo overseas trip was at the direct invitation of the german chancellor. do you consider yourself a feminist? angela merkel‘s official agenda... interesting reaction! . . .empowering women and charming one in particular. berlin wants, needs, stronger ties to the trump administration. translation: it's the strategy of dialogue, that's the most important thing. you can reach trump through his daughter. every woman should do things by her own, by her own status and by her own positions, and not because of her father's position. what you're seeing here may well mark a profound shift in the way that germany, europe, does business with the united states. ivanka trump wields significant influence with her father. the relationship that angela merkel and other leaders strike with the first daughter will be closely scrutinised on both sides of the atlantic. expect to see more of the first daughter on the international stage. in the age of trump, it seems, family comes first. jenny hill, bbc news, berlin. our top story this evening. theresa may takes the tory campaign to wales, challenging labour in its heartland. still to come: british boxer anthonyjoshua prepares for saturday's epic bout at wembley. coming up in sportsday on bbc news: we'll have the challenge cup sixth round draw live. who will holders hull fc face? as well as huddersfield's conquerors swinton, featherstone, dewsbury and barrow will all want big teams. it's the technological issue of our time — the rise of artificial intelligence and the extraordinary rate of progress in the way machines can learn. the latest example is an app that will be better at medical diagnosis than a human doctor, at least that's what its developers claim. too good to be true or another worrying step towards a world in which machines run the show? our technology correspondent, rory cellan jones, has been finding out. how can i help today? dr hannah allen is seeing a patient. this consultation is happening inside a technology company with an ambitious mission. ba bylon company with an ambitious mission. babylon is building a computer program which should be able to diagnose your problem at least as well as your gp. could you specify the regions where you have pain. the computer has been given the same information as the doctor and reaches the same conclusion. it's quite likely you may be suffering from something called potentially gallstones. 0k. from something called potentially gallstones. ok. my tummy hurts. i'm sorry you're feeling unwell. there isa sorry you're feeling unwell. there is a long way to go. there should be a smartphone app that you could talk to. you will have one personal doctor who will sit—in your pocket and monitors all your time. doctor who will sit—in your pocket and monitors all yourtime. he doctor who will sit—in your pocket and monitors all your time. he can talk to you and diagnose you and see and predict your future. where is the pain in your stomach. this combines medicine with the latest trends in computer science. babylon is using something called machine learning where a computer is given vast amounts of data and teaches itself a task. the same technique is being used here to recognise what i'm saying. mostly accurately. we're already seeing machine learning popping up in all sorts of other places. machine learning is all about giving lots and lots of data to a computer and then the computer learns from that data to be able to do the specific tasks, essentially. so the machine learns from data. so there's really a whole range of areas where we have more and more access to data, so that could be in the medical field, it could be in education, it could be for solving societal challenges. it's what gives you personalised recommendations on shopping sites. it helped a computer beat a champion player of a complex chinese game, go, and machine learning is powering the software behind driveless cars, but there are concerns about these machines removing the human touch from many areas of our lives and costing jobs. i don't feel like it's going to put me out of a job. i think it's going to work really nicely alongside of gps. for me, i love seeing patients, i love being able to listen to patients' complaints and to be able to come up with, you know, solutions to their problems. are you sweating more than usual? computers can learn much faster and much more than we can. but let's face it, they're never going to have much of a bed side manner. can i confirm your gender, please. rory cellan—jones, bbc news. thank you. the french president has called for unity in what he said would be a long and difficult fight against terrorism. francois hollande made the remarks at a ceremony to honour the policeman shot dead in paris last week. xavierjugele, who was 37, was killed when a gunman opened fire on the champs elysees. facebook has been criticised after a thai man live streamed video of himself killing his daughter and then taking his own life. facebook says it was an "appalling" incident and has removed the content. it comes after a man in the us murdered someone on the livestreaming service. the parents of madeleine mccann say they will never give up searching for their missing child and described the tenth anniversary of her disappearance, next week, as a "a horrible marker of stolen time." madeleine vanished while on holiday in portugal with her parents and siblings on the 3rd may 2007. our home affairs correspondent, tom symonds, is outside new scotland yard. tom, what has kate mccann been saying? well, kate and gerry mccann put out a statement in the last 24—hours ahead of this tenth anniversary of madeleine's disappearance. they have said, as you say, it will be a stressful time for them not least because of the publicity that will come along as a result of this anniversary. publicity they have been concerned about misinformation and down right lies they say about this case that have been publicised in the past. they have said however that they welcome what they call the warmth, encouragement and positivity they've experienced from the quiet majority of their supporters over the last ten years. they say kind, decent people have helped them along the way. this remains a missing persons inquiry because the police have no definitive evidence that madeleine mccann is dead. she would be a teenager by this point. their investigation continues. 0nce teenager by this point. their investigation continues. once it consumed the time of 30 officers, now they are down to four officers and they continue to follow leads. we're expecting the metropolitan police to say a little more about their work later tonight. really, this has been an extraordinary case. 0bviously, deeply disturbing. 0verly and heavily reported in the past and, of course, stubbornly unsolved to this date. george. tom, thank you very much. sir eltonjohn has cancelled a series of shows in america afterfalling ill with what's been described as a potentially deadly bacterial infection. sir elton, who's 70, spent two nights in intensive care after contracting the illness while on tour in chile earlier this month. he's now recovering at home in britain. police in richmond, in south—west london, have confirmed that the actor, tom hardy, helped them apprehend a teenager suspected of crashing a stolen moped. eyewitnesses described how the 39—year—old star of action movies became involved in a hollywood—style chase after the moped passed through a red light and collided with another vehicle. it'll be one of the biggest boxing bouts in recent times, at stake will be two heavyweight titles. on saturday, 90,000 spectators will see britain's anthonyjoshua, who won super heavyweight gold at the 2012 london olympics, take on ukraine's wladimir klitschko at wembley stadium. 0ur sports editor, dan roan, has been watching anthony joshua's preparations. there's some flash photography in his report. final preparations for the fight of his life. regarded as the man heavyweight box‘s been crying out for, anthonyjoshua is on the verge of becoming the sports biggest star. and, having granted us access to his training camp... how are you doing, bro? how are you, sir, are you well? ..he told me just what it takes to become a champion. i've broken my ribs before, my hand. you know, i've dislocated shoulders and stuff in the gym, but we get it right for the fight. the coach's try to reveal your potential and then it becomes a bit of an ordeal because they start pushing you to places that you've never been before. this is a new level, is it, for you? ijust a whole new level, completely. right. especially with the type of fight we're in as well. joshua has come a long way in a short space of time. london 2012 olympic champion, since turning professional he's unbeaten and now stands to earn in excess of £10 million from saturday's showdown. so has fame and fortune changed him? i'm in the same flat that i've been in since in 2011. so far, the simple life has worked. where we grew up, everyone was about making money, when we were young, but it was about being low—key. understated. probably didn't want to get your house burgled, do you now know what i mean? but life hasn't always been trouble—free. joshua's brushes with the law as a teenager, growing up in a tough part of london, are portrayed in a new advertising campaign which charts his rise to the top. it's just mistakes. what people can relate to is life, journeys and what people go through. everyone goes through different struggles, so i'm just showing mine and it can connect to a certain group of people and it got across my message. this is the kind of preparation and dedication that's taken anthonyjoshua to the brink of sporting superstardom and he knows that if he can now win the biggest fight of his career, he'll go to a whole new level altogether. high in the austrian mountains, the man who stands injoshua's way is completing his build—up. for a decade, 41—year—old ukrainian, wladimir klitschko, dominated the heavyweight division, but after losing his last fight says he's obsessed with victory. now i have a chance against young man, very ambitious, very athletic and a newcomer, a new star in boxing and heavyweight division. biggest stage they've ever had. the respectful build—up to this fight contrasts starkly with the antics, the trash talk and the brawls that have frequently brought boxing into disrepute. it's needed now and again, but it's got to be real because i don't take boxing as an act. this isn't like an act for me, this is a way of expressing myself and being true to myself. joshua's wasted little time in his road to the top. too good to be true, we're about to find out. dan roan, bbc news, sheffield. the olympic cycling champions jason and laura kenny have been to buckingham palace to receive their cbes. jason's won six 0lympic titles while laura's won four. they've both been named in the latest great britain cycling squad in preparation for the toyko olympics in 2020. earlier this year, laura kenny announced she was pregnant with their first child. time for a look at the weather, here's jay wynne. thank you. good evening a mix bag through the day today. there was sunshine to be had, but sharp showers, and thunder, some rain, sleet and significant snow in the highlands of scotland. it's lying on the ground there. some of us started ona the ground there. some of us started on a bright note, it was chilly. shower clouds developed and have been spreading south through the day on that cold northerly wind. another cold night ahead of us. there will bea cold night ahead of us. there will be a frost, once again. we are not done with the wintry showers just yet. there will be showers to much of england and wales in particular, one or two for scotland and northern ireland. they will fade away from western areas. the winds will be lighter, too. that is where the lowest temperatures will be, there will be wide spread frost in rural areas and just above freezing in the towns and cities. bright start for the south—west of england and wales too, most places will be dry with sunshine. more cloud for the midlands, eastern england and early showers to eastern coasts. much of northern england, northern ireland and scotland starts with sunshine. it will be cold and frosty. showers to the north and west of scotland, rain through the morning. the main focus for showers will be central and eastern parts of england tomorrow. they will be heavy and thundery. further west the showers are fewer and further between. dry with sunny spells. 11—12 degrees for england and wales, single digits for scotla nd england and wales, single digits for scotland and northern ireland. tomorrow evening, the showers will slowly fa d e tomorrow evening, the showers will slowly fade way from england and wales. it will pick up more cloud and rain to scotland and northern ireland. that will be a feature of things on thursday. temperatures on thursday up by a degree or so for england and wales, two or three degrees for scotland and northern ireland. george. thank you very much. a reminder of our main story: theresa may has taken to tory campaign to wales, challenging labour in its heartland. that's all from the bbc news at six, so it's goodbye from me, and on bbc one we nowjoin the bbc‘s news teams where you are. hello. this is bbc news. the headlines. theresa may says every vote for the tories will "strengthen her hand" in the brexit negotiations, as she campaigns in labour's heartlands in south wales. a vote for any other party would be a vote for a weak and failing jeremy corbyn, propped up by a coalition of chaos which would risk our national future. the shadow brexit secretary says labour would scrap the prime minister's brexit plans — and unilaterally guarantee the rights of eu citizens in the uk — if it wins power. the liberal democrat leader tim farron says he does not think gay sex is a sin — clarifying a question he had refused to answer several times so far during the election campaign. a number of well—known names — including jeffrey archer and kevin keegan — have settled phone—hacking claims against mirror group newspapers. in a moment it will be time for sportsday but first a look at what else is coming up this evening on bbc news. we'll be discussing theresa may's visit to south wales where she's hoping to stomp all over labour's traditional territory. we'll be getting reaction to the un secretary general‘s warning that an entire generation of children in yemen is being starved