the ups and downs of frequent mood swings can plunge you into deep, depressive lows. (crying) take you to uncontrollable highs. (muffled arguing) or, make you feel both at once. overwhelmed by bipolar i symptoms? ask about vraylar. some medications only treat the lows or the highs. vraylar effectively treats depression, acute manic and mixed episodes of bipolar i. full-spectrum relief of all symptoms. with just one pill, once a day. elderly patients with dementia-related psychosis call your doctor about unusual changes in behavior or suicidal thoughts. antidepressants can increase these in children and young adults. report fever, stiff muscles, or confusion, muscle movements, may be permanent. side effects may not appear for several weeks. metabolic changes may occur. movement dysfunction, restlessness, sleepiness, stomach issues are common side effects. when bipolar i overwhelms, vraylar helps smooth the ups and downs.