Once Upon a Time in Hollywood). We will also see Neve Campbell as Screamfranchise final Girl extraordinaire Sidney Prescott. David Arquette and Courteney Cox return as Dewey Riley and Gale Weathers; also Marley Shelton returns as Scream 4 character Deputy Judy Hicks. We will also see new cast members Jack Quaid (“The Boys”), Jenna Ortega (“You”). Scream will follow a woman returning to her home town to try to find out who has been committing a series of vicious crimes. If we continue along dearly departed Randy’s horror franchise logic, this may prove to be the most unpredictable and shocking series entry we have ever seen.