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Top News In பல்கலைக்கழகம் ஆஃப் மிச்சிகன் ரோஜல் புற்றுநோய் மையம் Today - Breaking & Trending Today

New study aims to improve anti-cancer drug response predictions across cancer types

New study aims to improve anti-cancer drug response predictions across cancer types
The goal of precision oncology is to be able to tailor treatments to each individual patient based on their cancer s unique molecular fingerprints.
New technologies and large, -omics datasets are now allowing researchers to examine shared features not just within a single type of cancer -; such as breast cancer -; but to look for patterns across many types of cancer. These data offer great clues that an approach that has shown success in one type of cancer may also work well against a different type of cancer based on common underlying features. ....

United States , Matthew Soellner , John Lloyd , Emily Henderson , Um College Of Literature , Study Co , University Of Michigan Rogel Cancer Center , Research Of Computational Medicine , University Of Michigan , Michigan Rogel Cancer Center , Study Co Senior Author , Human Genetics , Associate Chair , Computational Medicine , Michigan Medicine University , Sofia Merajver , Gum College , Breast Cancer , Liver Cancer , Mek Inhibitor , ஒன்றுபட்டது மாநிலங்களில் , மேத்யூ சோேல்ல்நேர் , ஜான் லாயிட் , எமிலி ஹென்டர்சன் , உம் கல்லூரி ஆஃப் இலக்கியம் , படிப்பு இணை ,

Combination treatment for common glioma type shows promise in mice

NIH-funded preclinical study suggests new approach to treat a type of brain tumor
Artist’s rendering of a glioma cell under attack from the immune system.Ella Marushchenko
What
Gliomas are common brain tumors that comprise about one third of all cancers of the nervous system. In a study funded by the National Institutes of Health, researchers tested a novel combination treatment approach on mice with tumors with characteristics similar to human astrocytomas a type of slow-growing glioma and found tumor regression in 60 percent of the mice treated. These encouraging results, published in the Journal of Clinical Investigation, could be the first step toward developing a treatment for this type of brain cancer. ....

Ann Arbor , United States , Maria Castro , Jane Fountain , Pedro Lowenstein , Ella Marushchenko , Us Department Of Health , Human Services , National Institutes Of Health , American Brain Tumor Association , University Of Michigan , Department Of Neurosurgery , Pediatric Brain Tumor Foundation , University Of Michigan Rogel Cancer Center , Rogel Comprehensive Cancer Center , National Institute Of Neurological Disorders , National Institutes , Clinical Investigation , Michigan Rogel Cancer Center , National Institute , Neurological Disorders , Hydroxyglutarate Elicits Metabolic Reprogramming , Happy Hearts , Chad Tough , ஆண்டு ஆர்பர் , ஒன்றுபட்டது மாநிலங்களில் ,

New urine test could avoid unnecessary prostate cancer biopsies

A urine test based on University of Michigan Rogel Cancer Center research could have avoided one third of unnecessary prostate cancer biopsies while failing to detect only a small number of cancers, according to a validation study that included more than 1,500 patients. ....

United States , Jeffrey Tosoian , Emily Henderson , University Of Michigan Rogel Cancer Center , Michigan Rogel Cancer Center , Study Lead Author , Clinical Lecturer , Prostate Cancer , Blood Test , Prostate Specific Antigen , Urine Test , ஒன்றுபட்டது மாநிலங்களில் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் ரோஜல் புற்றுநோய் மையம் , மிச்சிகன் ரோஜல் புற்றுநோய் மையம் , படிப்பு வழி நடத்து நூலாசிரியர் , மருத்துவ விரிவுரையாளர் , ப்ராஸ்டேட் புற்றுநோய் , இரத்தம் சோதனை , சிறுநீர் சோதனை ,

Study: New prostate cancer test could avoid unnecessary biopsies

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A urine test based on University of Michigan Rogel Cancer Center research could have avoided one third of unnecessary prostate cancer biopsies while failing to detect only a small number of cancers, according to a validation study that included more than 1,500 patients. The findings appear in the March issue of the
Journal of Urology.
The MyProstateScore test, which is being commercialized by LynxDX, a U-M startup company, measures levels of cancer-specific genes in a patient s urine. It is based on U-M research that discovered that half of all prostate tumors harbor a certain genetic anomaly in which the genes TMPRSS2 and ERG relocate on a chromosome and fuse together creating an on-switch for prostate cancer development. ....

United States , Nicholasw Eyrich , Rachel Botbyl , Gary Longton , Javed Siddiqui , Scotta Tomlins , Balaji Pandian , Zoey Chopra , Yashars Niknafs , Lakshmip Kunju , Toddm Morgan , Johnt Wei , Ganeshs Palapattu , Yingye Zheng , Daniele Spratt , Jeffrey Tosoian , Brucej Trock , Johns Hopkins University , National Cancer Institute Prostate , A Alfred Taubman Medical Research Institute , Early Detection Research Network , Um Precision Health Research Scholar Award , University Of Michigan Rogel Cancer Center , Fred Hutchinson Cancer Research Institute , Prostate Cancer Foundation , Career Enhancement Program ,

Farming natural killer exosomes to fight cancer

Farming natural killer exosomes to fight cancer
New research published in
Advanced Science from scientists at the University of Michigan Rogel Cancer Center and U-M College of Engineering highlights development in cancer-fighting efforts. The research details how the exosomes of natural killer cells (NK cells) can be targeted, harvested, and redirected to attack cancer cells.
Exosomes are small sacs of proteins and other molecules that are naturally released by almost every type of cell in the body, says co-author Yoon-Tae Kang, Ph.D. In this case, we wanted to expand our understanding of NK exosomes and try to harness their cancer-killing potential. ....

Sunitha Nagrath , University Of Michigan Rogel Cancer Center , Um College Of Engineering , Advanced Science , Michigan Rogel Cancer Center , Gum College , Yoon Tae Kang , சுநித் நாகரத் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் ரோஜல் புற்றுநோய் மையம் , உம் கல்லூரி ஆஃப் பொறியியல் , மிச்சிகன் ரோஜல் புற்றுநோய் மையம் , உம் கல்லூரி , யூன் டே காங் ,