UTSW discovers protective 'acid wall' formed by cancer cells
Cancer cells release a significantly more concentrated level of acid than previously known, forming an “acid wall” that could deter immune cells from attack
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Cancer cells release a significantly more concentrated level of acid than previously known, forming an “acid wall” that could deter immune cells from attack
E-Mail Researchers at Baylor College of Medicine and collaborators at other institutions have discovered that POT1, a gene known to be associated with risk of glioma, the most common type of malignant brain tumor, mediates its effects in a sex-specific manner. Researchers found that female mice with glioma that lacked the gene survived less than males. This led them to investigate human glioma cells, where they found that low POT1 expression correlated with reduced survival in females. Published in the journal Cancer Research, the study also shows that, compared to males', female tumors ha...