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Combination of tumor cell vaccine and checkpoint therapy creates effective immune response


Combination of tumor cell vaccine and checkpoint therapy creates effective immune response
A personalized tumor cell vaccine strategy targeting Myc oncogenes combined with checkpoint therapy creates an effective immune response that bypasses antigen selection and immune privilege, according to a pre-clinical study for neuroblastoma and melanoma. The neuroblastoma model showed a 75% cure with long-term survival, researchers at Children s National Hospital found.
Myc is a family of regulator genes and proto-oncogenes that help manage cell growth and differentiation in the body. When Myc mutates to an oncogene, it can promote cancer cell growth. The Myc oncogenes are deregulated in 70% of all human cancers. ....

Xiaofang Wu , Emily Henderson , Sheikh Zayed Institute For Pediatric Surgical Innovation , Children National Hospital , National Hospital , Sheikh Zayed Institute , Pediatric Surgical Innovation , Immune Response , எமிலி ஹென்டர்சன் , ஷேக் ஸேயெட் நிறுவனம் க்கு குழந்தை அறுவை சிகிச்சை கண்டுபிடிப்பு , குழந்தைகள் தேசிய மருத்துவமனை , தேசிய மருத்துவமனை , ஷேக் ஸேயெட் நிறுவனம் , குழந்தை அறுவை சிகிச்சை கண்டுபிடிப்பு , நோய் எதிர்ப்பு சக்தி பதில் ,

Backed by millions in public and private cash, rapid Covid tests are coming to stores near you


Backed by millions in public and private cash, rapid Covid tests are coming to stores near you
Scientists and lawmakers agree that over-the-counter Covid tests could allow desk workers to settle back into their cubicles and make it easier to reopen schools and travel.
But even as entrepreneurs race their products to market, armed with millions of dollars in venture capital and government investment, the demand for Covid testing has waned. Manufacturing and bureaucratic delays have also kept rapid tests from hitting store shelves in large numbers, though the industry was energized by the Food and Drug Administration s greenlighting of two more over-the-counter tests Wednesday. ....

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CDC and NIH launch community COVID-19 testing initiative


CDC and NIH launch community COVID-19 testing initiative
The Centers for Disease Control and Prevention (CDC), in collaboration with the National Institutes of Health (NIH), has launched an innovative community health initiative called Say Yes! COVID Test starting in Pitt County, North Carolina, and coming soon to Chattanooga/Hamilton County Tennessee. As many as 160,000 residents across the two communities will have access to free, rapid antigen tests that they can administer themselves to use three times a week for one month. NIH will provide the tests (also called a home-test or at-home test) and evaluate the effectiveness of the initiative, which aims to determine if frequent self-administered COVID-19 testing helps residents reduce community transmission of SARS-CoV-2, the virus that causes COVID-19 disease. ....

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