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UNC Charlotte researchers analyzed the host origins of SARS-CoV-2 and other coronaviruses

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IMAGE: This tree is a summary of the selected host transformations in the clade of Betacoronavirus associated with SARS-CoV, MERS-CoV, and SARS-CoV-2. Bats have been fundamental hosts of these human coronaviruses..
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Credit: Denis Jacob Machado
Coronavirus (CoVs) infection in animals and humans is not new. The earliest papers in the scientific literature of coronavirus infection date to 1966. However, prior to SARS-CoV, MERS-CoV, and SARS-CoV-2, very little attention had been paid to coronaviruses.
Suddenly, coronaviruses changed everything we know about personal and public health, and societal and economic well-being. The change led to rushed analyses to understand the origins of coronaviruses in humans. This rush has led to a thus far fruitless search for intermediate hosts (e.g., civet in SARS-CoV and pangolin in SARS-CoV-2) rather than focusing on the important work, which has always been surveillance of SARS-like viruses in bats ....

Carol Grotnes Belk , Daniela Janies , Denis Jacob Machado , University Of North Carolina At Charlotte , Bioinformatics Research Center , North Carolina , Carol Grotnes Belk Distinguished Professor , Infectious Emerging Diseases , Disease In The Developing World , பல்கலைக்கழகம் ஆஃப் வடக்கு கரோலினா இல் சார்லோட் , உயிர் தகவலியல் ஆராய்ச்சி மையம் , வடக்கு கரோலினா ,

Researchers perform a comprehensive analyses to clarify the origins of coronaviruses

Coronavirus (CoVs) infection in animals and humans is not new. The earliest papers in the scientific literature of coronavirus infection date to 1966. However, prior to SARS-CoV, MERS-CoV, and SARS-CoV-2, very little attention had been paid to coronaviruses. ....

Carol Grotnes Belk , Daniela Janies , Denis Jacob Machado , Emily Henderson , University Of North Carolina At Charlotte , Bioinformatics Research Center , North Carolina , Jacob Machado , First Author , Carol Grotnes Belk Distinguished Professor , Ars Cov 2 , Ers Cov , Public Health , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் வடக்கு கரோலினா இல் சார்லோட் , உயிர் தகவலியல் ஆராய்ச்சி மையம் , வடக்கு கரோலினா , ஜாகோப் மச்சாடோ , முதல் நூலாசிரியர் ,

New technology enables faster and more accurate tracing of COVID-19 and other viruses

Jeremy Edwards, director of the Computational Genomics and Technology (CGaT) Laboratory at The University of New Mexico, and his colleagues at Centrillion Technologies in Palo Alto, Calif. and West Virginia University, have developed a chip that provides a simpler and more rapid method of genome sequencing for viruses like COVID-19. ....

United States , Jeremy Edwards , Emily Henderson , Department Of Chemistry , Virginia University , University Of New Mexico , American Chemical Society Langmuir , Technology Cgat Laboratory , Computational Genomics , New Mexico , Centrillion Technologies , Palo Alto , West Virginia University , Accurate Chip Based Resequencing , American Chemical Society , Ars Cov 2 , ஒன்றுபட்டது மாநிலங்களில் , ஜெர்மி எட்வர்ட்ஸ் , எமிலி ஹென்டர்சன் , துறை ஆஃப் வேதியியல் , வர்ஜீனியா பல்கலைக்கழகம் , பல்கலைக்கழகம் ஆஃப் புதியது மெக்ஸிகோ , கணக்கீட்டு மரபியல் , புதியது மெக்ஸிகோ , பாலோ ஆல்டோ , மேற்கு வர்ஜீனியா பல்கலைக்கழகம் ,

TBI: A new roadmap for advancing personalized treatment solutions

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NEW YORK, NY (April 26, 2021) -Brain research and advocacy nonprofit Cohen Veterans Bioscience (CVB) today announced the launch of a National TBI Precision Solutions Research Roadmap, with the advent of the first in a series of publications resulting from its Brain Trauma Blueprint framework program.
The Brain Trauma Blueprint is a framework that enables stakeholder groups across government, academia, foundations, and industry to advance precision diagnostics and treatments for brain trauma through a coordinated effort. The framework comprises a 12-step process to jointly identify unmet patient needs, associated research priorities, landscape state of the science, identify research gaps and barriers, and provide recommendations for progress. The framework also provides a call to action for funders and collaborators across the broader stakeholder community to engage in a transparent & coordinated network. ....

United States , University Of Utah , Salt Lake , Jeffrey Humpherys , Jamshid Ghajar , Mary Katherine Mccafferty , Eamonn Kennedy , Ericm Prager , Michael Mccrea , Adamr Ferguson , Lee Lancashire , Mary Jo Pugh , Angela Lumba Brown , Kristinec Yaffe , University Of Utah School Medicine , Phd Medical College Of Wisconsin , Analytic Science Center , Department Of Medicine , Division Of Epidemiology , Cohen Veterans Bioscience , Solutions Research Roadmap , Brain Trauma Blueprint , Information Officer , Personalized Approach , Traumatic Brain Injury , Utah School ,

Chinese hazelnut: The newest piece in the hazelnut genome puzzle

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IMAGE: The ability of a high-quality genome for a hazelnut species provides resources for high-precision molecular breeding instead of the traditional empirical breeding methods.
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Credit: Hoticulture Research
Humans have been breeding plants for their economic value for thousands of years. Traditionally, plant breeding techniques included cumbersome and time-consuming techniques like grafting and hybridization to enhance traits of economic value like disease resistance and high nutrition content. Now, with the ability to edit plant DNA using revolutionary gene-editing tools, particularly the CRISPR-Cas9 system, it is possible to enhance traits of economic value in plants easily and more efficiently than by using traditional techniques. But for that, it is necessary to sequence whole genomes of economically important crops and identify all the genes controlling these desirable traits. ....

Jiao Yang , Ying Wu , Yongzhi Yan , Yong Zhi Yang , Pengchuan Sun , Zhenyue Wang , Jianxiang Ma , Jianquan Liu , Zhiqiang Lu , Ying Li , Jinyuan Chen , Zeyu Zheng , Horticulture Research , Key Laboratory Of Grassland Agro , College Of Life Sciences , Sichuan University , Lanzhou University , Key Laboratory Of Bio , Key Laboratory , Grassland Agro Ecosystem , Innovation Ecology , Life Sciences , State Key Laboratory , Mountain River Engineering , Plant Sciences , ஜியாவோ யாங் ,