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Database developed on key mollusk to study pollution in coastal areas


Credit: University of Córdoba
Scrobiculariaplana is a type of wedge clam widely found along the coasts and estuariesof northern Europe, the Mediterranean and West Africa. Like other mollusks, it is used as a bioindicator to study pollution in these types of ecosystems, for its ability to accumulate heavy metals and organic pollutants.
A new study has managed to identify the transcriptome and the associated proteome of this bivalve, a finding that could represent an important leap forward in the early detection of pollutants in coastal areas. While the genome is the DNA content comprising the genetic information essential for life, the transcriptome includes only the information on genes that are expressed, while the proteome is the totality of proteins expressed at a given time and under specific conditions. Therefore, its reconstruction is key to understanding the molecular effects of pollution. ....

Ministry Of Economy , Central Research Support Service , University Of Cordoba , Institute Of Marine Sciences Andalusia , Marine Sciences , Stress Response , Carmen Mich , Professor Jos , State Program , அமைச்சகம் ஆஃப் பொருளாதாரம் , பல்கலைக்கழகம் ஆஃப் கார்டோபா , கடல் அறிவியல் , மன அழுத்தம் பதில் , ப்ரொஃபெஸர் ஜோஸ் , நிலை ப்ரோக்ர்யாம் ,

Massive fragment screen points way to new SARS-CoV-2 inhibitors


Experiment with 2533 fragments compounds generates chemical map to future antiviral agents 
Principal Beamline Scientist on I04, Frank von Delft. 
New research published in
Science Advances provides a template for how to develop directly-acting antivirals with novel modes of action, that would combat COVID-19 by suppressing the SARS-CoV-2 viral infection. The study focused on the macrodomain part of the Nsp3 gene product that SARS-CoV-2 uses to suppress the host cell’s natural antiviral response. This part of the virus’s machinery, also known as Mac1, is essential for its reproduction: previous studies have shown that viruses that lack it cannot replicate in human cells, suggesting that blocking it with a drug would have the same effect.   ....

University Of Oxford , Structural Biology Consortium , University Of California San Francisco , Beamline Scientist , Science Advances , Biology Consortium , California San , Drug Discovery , Medicinal Chemistry , Antiviral Drug , Molecular Modelling , Natural Sciences , Protein Structure , X Ray Crystallography , பல்கலைக்கழகம் ஆஃப் ஆக்ஸ்ஃபர்ட் , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா சான் பிரான்சிஸ்கோ , உயிரியல் கூட்டமைப்பு , கலிஃபோர்னியா சான் , உயிர் தகவலியல் , மருந்து கண்டுபிடிப்பு , மருத்துவ வேதியியல் , மூலக்கூறு மாடலிங் , இயற்கை அறிவியல் , ப்ரோடீந் அமைப்பு ,

ROSALIND, HELiXrUS and Geninus Partner to Bring Powerful New Single Cell Analysis Services to Cancer Researchers


Press release content from Business Wire. The AP news staff was not involved in its creation.
ROSALIND, HELiXrUS and Geninus Partner to Bring Powerful New Single Cell Analysis Services to Cancer Researchers
April 15, 2021 GMT
SAN DIEGO & SEOUL, South Korea (BUSINESS WIRE) Apr 15, 2021
ROSALIND ®, a software leader in extracting meaningful insights from diverse pools of life science data, today announced that it has partnered with two Seoul-based technology providers to enable a powerful new Single Cell data analysis solution for cancer research scientists in Asia. Geninus, a leading full-service genomics laboratory, will combine the ROSALIND platform with its Celinus™ single cell RNA sequencing service to enable expanded analysis and interpretation of data, as well as seamless sharing and collaboration across labs and geographies. HELiXrUS, a channel partnership company focused on biological big data and multi-omics, played a leading role in establishing this p ....

Soult Ukpyolsi , South Korea , United States , San Diego , Tim Wesselman , Colin Sanford , Geninu Celinus , Samsung Genome Institute , Helixrus Inc , Single Cell , Single Cell Analysis , Genome Biology , Single Cell Gene Expression , Single Cell Immune Profiling , Single Nucleus Gene Expression , Single Cell Multiome , Spatial Gene Expression , Cell Solution , Woong Yang Park , Business Wire , Products And Services , Scientific Research , Pharmaceutical Manufacturing , Health Care Industry , Data Management , New Products And Services ,

Dog Tests Positive for SARS-CoV-2, UConn Surveillance Finds


Date Time
Dog Tests Positive for SARS-CoV-2, UConn Surveillance Finds
Over 100 dogs and cats have tested positive in the United States; this is the first domestic animal in Connecticut to test positive
Zeinab Helal micropipettes samples the Connecticut Veterinary Medical Diagnostic Laboratory. (Peter Morenus/UConn Photo)
Since the start of the pandemic, over 100 domestic dogs and cats have tested positive for SARS-CoV-2 in the United States. The first reported detection of the virus in a dog in Connecticut has been confirmed by Connecticut Veterinary Medical Diagnostic Laboratory (CVMDL) diagnosticians as a result of their surveillance for SARS-CoV-2 in dogs and cats. The findings are documented in a pre-print article published earlier this month. ....

South Africa , United States , United Kingdom , Guillermo Risatti , Zeinab Helal , Salvatore Frasca , Dong Hun Lee , Peter Morenus Uconn , National Animal Health Laboratory Network , Department Of Pathobiology , Molecular Epidemiology Research Ga , Connecticut Veterinary Medical Diagnostic Laboratory , Connecticut Veterinary Medical Diagnostic , Veterinary Science Professor Guillermo Risatti , Professor Dong Hun Lee , Molecular Epidemiology Research , University Of Connecticut , Infectious Disease , Public Health , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் , சால்வடோர் ப்ரஸ்கா , டாங் ஹன் லீ , தேசிய விலங்கு ஆரோக்கியம் ஆய்வகம் வலைப்பின்னல் , கனெக்டிகட் கால்நடை மருத்துவ கண்டறியும் ஆய்வகம் , மூலக்கூறு தொற்றுநோய் ஆராய்ச்சி ,