Can SARS-CoV-2's impairment of endothelium cause vascular disease?
Can SARS-CoV-2’s impairment of endothelium cause vascular disease? The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen that causes the coronavirus disease (COVID-19), contains the spike protein that binds with the human angiotensin-converting enzyme 2 (ACE2) receptor to enter and infect host cells. Researchers in the U.S. and China have revealed that SARS-CoV-2's spike protein does not only latch and bind to healthy cells for infection, but also plays a key role in the disease process. The study, published in the journal Circulation Research, suggests that COVID-...