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COVID-19: 2 mutated strains of the virus discovered in India


The variants, called AN440K and E484Q, have been found circulating in a few districts of Maharashtra, Kerala and Telangana, the Ministry said.
It was a given fact that the COVID-19 virus will mutate, as does all viruses. But what scientists were not sure was just how lethal or benign these mutations will turn out to be. In the case of COVID-19, the UK, South African and Brazilian variants show that these mutations may, indeed, be cause for worry. The Union Health Ministry on Tuesday confirmed the detection of two new variants of the novel coronavirus in at least three Indian states. These variants are not the ones that originated from Brazil, the UK and South African. The variants, called AN440K and E484Q, have been found circulating in a few districts of Maharashtra, Kerala and Telangana, the Ministry said. The confirmation comes against the backdrop of Maharashtra and Kerala reporting an upsurge in COVID-19 cases, and both states accounting for more than 75 per cent of overall active caseload of the country, as of Tuesday.

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Over 7,000 SARS-CoV-2 mutations documented. But mutants different from variants, say scientists


Over 7,000 SARS-CoV-2 mutations documented. But mutants different from variants, say scientists 
Over 7,000 SARS-CoV-2 mutations documented. But mutants different from variants, say scientists 
Scientists said that 7,684 mutations in the SARS-CoV-2 genome were documented from the data analysis of 6,017 genomes sequenced so far, however, they added that this doesn't mean 7,000 variants are going around in the country.
"That doesn't mean 7,000 variants are going around in the country.
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File image for representation: Reuters
More than 7,000
SARS-CoV-2 mutations have been documented but that doesn't translate to variants, say scientists, emphasising the distinction between the two and cautioning that the spike in cases in some states is likely due to non-adherence of Covid-19 appropriate behaviour.

Madhya-pradesh , India , Hyderabad , Andhra-pradesh , United-kingdom , Brazil , Kolkata , West-bengal , South-africa , Telangana , Chhattisgarh , Kerala

NIBMG study links protein to slower spread of mutant coronavirus in Asia


Updated Feb 09, 2021 | 09:05 IST
AAT protein deficiency can lead to higher levels of neutrophil elastase in the cells, enabling the coronavirus to spread faster.
NIBMG study links protein to slower spread of mutant coronavirus in Asia  |  Photo Credit: iStock Images
New Delhi: A deficiency in a human protein has been linked to a slower spread of a mutant of the novel coronavirus in Asia. A team of scientists at the National Institute of Biomedical Genomics (NIBMG), Kalyani, suggested that there could be a biological reason behind the slower spread of the mutant coronavirus - D614G - in Asia compared to Europe and the USA.

Kolkata , West-bengal , India , Kalyani , Karnataka , United-states , New-delhi , Delhi , Americans , America , Partha-majumder , Nidhan-biswas

COVID-19: Second case of UK variant found in Wisconsin


The Wisconsin public health lab confirmed the second case of the U.K. variant of COVID-19 in the state.Continuing Coverage: Coronavirus in WisconsinThe Wisconsin Department of Health Services and laboratory partners identified the second variant strain of SARS-CoV-2 Saturday in Wisconsin.The first case was found in Eau Claire County last month.The particular variant, referred to as B.1.1.7, was first discovered circulating widely in England last November. "A new study out of the UK showed that the strain there may unfortunately be 35% more deadly than the conventional strain and up to 70% more contagious," Director of Medical Services of the Milwaukee County Office of Emergency Management Dr. Ben Weston said.State health officials said the second case of the variant was found in Waukesha County."The case that was detected in Waukesha County was identified after testing positive for COVID-19," Waukesha County Health Officer Benjamen Jones said in a statement. "That individual was successfully contact traced and instructed to isolate. We are working in cooperation with DHS to gather additional details to facilitate statewide monitoring."It's not clear whether the second patient had recently traveled.Based on epidemiologic and modeling studies, researchers believe the new strain spreads more rapidly and easily than the original strain of SARS-CoV-2. "It is concerning that we have identified a second case of a variant that spreads more easily. We are able to sequence a small proportion of tests collected which means in reality, there are likely many more cases of this variant in Wisconsin," said Dr. Ryan Westergaard, Chief Medical Officer in the DHS Bureau of Communicable Diseases. "All viruses evolve and develop new genetic mutations as they replicate, and sometimes the new mutations can make them more dangerous. Fortunately, we can prevent the virus from replicating and mutating – we can do this by consistently using all the tools we have for stopping the spread."In Wisconsin, the strain was identified through ongoing surveillance and whole-genome sequencing, a routine practice since the onset of the COVID-19 pandemic. Officials said all viruses, including the virus that causes COVID-19, change through mutation, and new variants of the virus are expected to occur over time. The first patient had recently traveled abroad. Now in the second year of the COVID-19 pandemic, molecular surveillance of SARS-CoV-2 will increase in importance to quickly identify and understand new variants, the DHS said."We will also be looking at that very carefully and following it carefully," Dr. Anthony Fauci said in January. "But right now, the data indicate that the UK mutant is still quite sensitive to the antibodies that are induced by the vaccine."Officials said the emerging mutations of SARS-CoV-2 may be more infectious and it is critically important to follow best public health practices, including wearing a mask, staying home, maintaining physical distance, and washing hands frequently. "They're around. They are not predominant at this point, most likely," said Dr. Matt Anderson with UW Health. "Will they become predominant or not? Hope not, but it certainly seems to be what we're seeing trending in other states and locations."According to the Centers for Disease Control, there have been at least 690 cases of the UK variant reported in 33 states.Sign up for coronavirus email alerts from WISNGet breaking news alerts with the WISN 12 app.Follow us: Facebook | Twitter | Instagram | YouTube

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UK variant of Covid-19 has mutated again: Scientists

UK Covid-19 variant has mutated. According to scientists, although this change may reduce vaccine effectiveness, the current ones in use should still work. The UK has already stepped up measures to control the spread of new variants as urgent testing for the South Africa variant is starting in parts of the country and travel restrictions have been introduced to stop more cases entering from abroad, the BBC reported on Tuesday.

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A new Covid-19 challenge: Mutations rise along with cases - The Hindu BusinessLine

The coronavirus is becoming more genetically diverse, and health officials say the high rate of new cases is the main reason

Brazil , Ann-arbor , Michigan , United-states , United-kingdom , Ohio-state-university , Ohio , China , South-africa , Britain , America , Adam-lauring

CDC issues warning on New COVID-19 variant B117


CDC issues warning on New COVID-19 variant B117
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"The coronavirus is doing what all viruses do, mutating as it goes," said Dr. Linda Yancey.
This new variant spreads 70% faster and is extremely contagious, but it is not more deadly than the COVID-19 strain.
The CDC issued a warning Friday that said this new variant could become the dominant source of infection in the U.S. by March and would likely lead to a wrenching surge in cases and deaths that would further burden overwhelmed hospitals.
By Saturday, authorities in Dallas and Corpus Christi reported the first known cases of the B117 variant in their communities.

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