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Repurposed drugs for COVID-19 treatment identified through virtual screening and cell-based assays A joint research group from KAIST and Institut Pasteur Korea has identified repurposed drugs for COVID-19 treatment through virtual screening and cell-based assays. The research team suggested the strategy for virtual screening with greatly reduced false positives by incorporating pre-docking filtering based on shape similarity and post-docking filtering based on interaction similarity. This strategy will help develop therapeutic medications for COVID-19 and other antiviral diseases more rapidly...

All Samsung semiconductor chip plants get Carbon Trust’s Triple Standard certification Samsung, the world’s biggest memory chip maker, has announced that all of its semiconductor chip plants have received British Carbon Trust’s Triple Standard certification. It means that all those plants are designed to reduce carbon and water waste, protecting the environment as much as possible. The South Korean firm has now become the world’s first company whose semiconductor manufacturing sites have received the Triple Standard certification from Carbon Trust. Samsung Foundry has a total of nine ...

Newly Engineered Bacterium can Produce Carminic Acid Written by AZoMApr 7 2021 A team of researchers from the Korea Advanced Institute of Science and Technology (KAIST) has designed a bacterium that can produce carminic acid—a natural red colorant that is extensively used in cosmetics and food. A schematic biosynthetic pathway for the production of carminic acid from glucose. Biochemical reaction analysis and computer simulation-assisted enzyme engineering were employed to identify and improve the enzymes (DnrFP217K and GtCGTV93Q/Y193F) responsible for the latter two reactions. Image Credit...

 E-Mail IMAGE: Figure: A schematic biosynthetic pathway for the production of carminic acid from glucose. Biochemical reaction analysis and computer simulation-assisted enzyme engineering was employed to identify and improve the enzymes (DnrFP217K... view more  Credit: KAIST A research group at KAIST has engineered a bacterium capable of producing a natural red colorant, carminic acid, which is widely used for food and cosmetics. The research team reported the complete biosynthesis of carminic acid from glucose in engineered Escherichia coli. The strategies will be useful for the de...