Stay updated with breaking news from Davida mcallister. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.
Objective To evaluate the impact of implementing a high sensitivity assay for cardiac troponin I on long term outcomes in patients with suspected acute coronary syndrome.
Design Secondary observational analysis of a stepped wedge, cluster randomised controlled trial.
Setting 10 secondary and tertiary care centres in Scotland, UK.
Participants 48 282 consecutive patients with suspected acute coronary syndrome. Myocardial injury was defined as any high sensitivity assay result for cardiac troponin I >99th centile of 16 ng/L in women and 34 ng/L in men.
Intervention Hospital sites were randomly allocated to either early (n=5 hospitals) or late (n=5 hospitals) implementation of a high sensitivity cardiac troponin I assay with sex specific diagnostic thresholds.
Main outcome measure The main outcome was myocardial infarction or death at five years.
Results 10 360 patients had cardiac troponin concentrations greater than the 99th centile, of w ....
In this multistate modelling analysis, Sida Chen and colleagues examine sociodemographic characteristics and longitudinal progression of multimorbidity using data from primary care records in England ....
Author summary Why was this study done? ➢ The EuroQol-5 dimension (EQ-5D) and SF-36 are questionnaire-based tools that combine measures of physical and mental health into overall quality of life scores. These scores are used in randomised controlled trials of drug treatments to estimate how treatments affect quality of life. These estimates then inform decisions about which treatments should be offered to people with specific conditions. ➢ Multimorbidity, the presence of 2 or more conditions, makes diagnosis and treatment more complex and is associated with worse quality of life in some settings. ➢ People with multimorbidity are underrepresented in clinical trials, and little is known about whether and how multimorbidity changes quality of life in clinical trials. This makes it difficult for clinicians and clinical guideline developers to determine how results from clinical trials should be applied to people with multimorbidity. What did the researchers do and find? ➢ To ....
Effect of Vaccination on Transmission of SARS-CoV-2 nejm.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from nejm.org Daily Mail and Mail on Sunday newspapers.
Weight gain and diabetes threaten progress in reducing heart attacks and strokes miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.