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Foghorn Therapeutics Provides First Quarter 2024 Financial and Corporate Update

Dose escalation in FHD-286 combination trial in AML continues to progress with clinical data expected in the second half of 2024; potential to be a first-in-class oral broad-based differentiation.

United statesUnited kingdomPeter kelleherGreg dearbornAdam silversteinKarin hellsvikAdrian gottschalkB degrader programKey recent program updatesAmerican association for cancer researchExchange commissionDegrader programTherapeutics incFoghorn therapeutics incDevelopment expensesCompany annual report on form

Kymera Therapeutics Presents Preclinical Data Demonstrating Activity of MDM2 Degraders in Acute Myeloid Leukemia and Merkel Cell Carcinoma

Preclinical models highlight the potential of KT-253 as a monotherapy and combined with the standard of care agent venetoclax for the treatment of Acute Myeloid Leukemia MDM2 degraders shown to.

United statesDana farber cancer instituteYogesh chutakeJustine koenigsbergVarsha ananthapadmanabhanJared gollobTodd cooperJamesa decaprioDepartment of medical oncologyDepartment of medicineCorporate affairsExchange commissionBoston globeDegrader programHarvard medical schoolInternational conference on molecular

Kymera Therapeutics Presents Preclinical Data Demonstrating Activity of MDM2 Degraders in Acute Myeloid Leukemia and Merkel Cell Carcinoma - Kymera Therapeutics (NASDAQ:KYMR)

Kymera Therapeutics Presents Preclinical Data Demonstrating Activity of MDM2 Degraders in Acute Myeloid Leukemia and Merkel Cell Carcinoma - Kymera Therapeutics (NASDAQ:KYMR)
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United statesDana farber cancer instituteJamesa decaprioVarsha ananthapadmanabhanYogesh chutakeJared gollobInternational conference on molecularKymera therapeutics incDepartment of medical oncologyHarvard medical schoolBoston globeDegrader programDepartment of medicineAcute myeloid leukemiaMolecular targetsCancer therapeutics

SK Biopharmaceuticals Proteovant Therapeutics Presents Preclinical Data on IKZF2 Protein Degrader Program and MOPEDtm Molecular Glue Screening Platform at the 20th Annual Discovery on Target Conference

SK Biopharmaceuticals, a global biotech focused on the research, development and commercialization of treatments for disorders of the central nervous system (CNS) and oncology, and its U.S. R&D subsidiary, Proteovant Therapeutics, today announced.

United statesSouth koreaSoult ukpyolsiDonghoon leeDina albaneseCorey stricklandHyoungrae choSk groupSk life science incSource sk biopharmaceuticals co ltdMost influential companiesSk biopharmaceuticals co ltdSk incProtein degrader programProteovant therapeutics presents preclinical dataDegrader program

Kymera Therapeutics Presents Data Demonstrating Superior Efficacy of KT-253, a Potent and Selective Heterobifunctional MDM2 Degrader, Compared to Small Molecule Inhibitor in Preclinical Leukemia Models at the European Hematology Association Congress

A single dose of KT-253 drives tumor regression and demonstrates differentiated pharmacology compared to small molecule inhibitor in preclinical models of ALL and AMLWATERTOWN, Mass., June 09, 2023 . | June 9, 2023

United statesNancy dumontBruce jacobsNello mainolfiTodd cooperChris brinzeyBoston globeCorporate affairsEuropean hematology associationExchange commissionKymera therapeutics incDegrader programPulse dosingSelective heterobifunctionalTumor regressionDemonstrates differentiated pharmacology compared