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New research finds connection: Inflammation, metabolism and scleroderma scarring

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Scleroderma, a chronic and currently incurable orphan disease where tissue injury causes potentially lethal skin and lung scarring, remains poorly understood.
However, the defining characteristic of systemic sclerosis, the most serious form of scleroderma, is irreversible and progressive scarring that affects the skin and internal organs.
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We found that scleroderma inflammation dramatically increases CD38, an enzyme that normally breaks down a metabolic nutrient, NAD+. When NAD+ levels decrease, tissue injury becomes chronic and progresses to scar formation rather than to healthy repair, says study author John Varga, M.D., division chief of rheumatology at Michigan Medicine.
According to the study, treatments that prevented NAD+ reduction in the mice, whether by boosting the levels of the nutrient genetically or pharmacologically, prevented scarring in the skin, lungs and abdominal wall. ....

United States , Johann Gudjonsson , John Varga , Michigan Medicine Scleroderma Program , Northwestern Scleroderma Program , University Of Michigan , Michigan Medicine , Scleroderma Program , Mayo Clinic , Cell Biology , Medicine Health , Metabolism Metabolic Diseases , Nutrition Nutrients , Researchers Scientists Awards , ஒன்றுபட்டது மாநிலங்களில் , ஜான் வர்கா , மிச்சிகன் மருந்து ஸ்க்லரோடெர்மா ப்ரோக்ர்யாம் , வடமேற்கு ஸ்க்லரோடெர்மா ப்ரோக்ர்யாம் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் , மிச்சிகன் மருந்து , ஸ்க்லரோடெர்மா ப்ரோக்ர்யாம் , மயோ சிகிச்சையகம் , செல் உயிரியல் , மருந்து ஆரோக்கியம் , தோல் நோய் , வளர்சிதை மாற்றம் வளர்சிதை மாற்ற நோய்கள் ,

Global Skin Cancer Dermatology Market Research Report 2021-2025

15/01/2021 - 09:52
Bharat Book Bureau Provides the Trending Market Research Report on “Global Skin Cancer Dermatology Market Research Report 2021-2025”under Life Sciences Category. The report offers a collection of superior market research, market analysis, competitive intelligence and Market reports.
The global Skin Cancer Dermatology Market Dermatologists are specially trained in detecting skin cancer. In the context of China-US trade war and COVID-19 epidemic, it will have a big influence on this market. Skin Cancer Dermatology Report by Material, Application, and Geography - Global Forecast to 2025 is a professional and comprehensive research report on the world’s major regional market conditions, focusing on the main regions (North America, Europe and Asia-Pacific) and the main countries (United States, Germany, United Kingdom, Japan, South Korea and China). ....

United States , South Korea , United Kingdom , Agilent Technologies , Life Sciences , Bharat Book Bureau , Bharat Book Bureau Provides , Trending Market Research Report , Skin Cancer Dermatology Market Research Report , Skin Cancer Dermatology Market Dermatologists , Cancer Dermatology Report , North America , Skin Cancer Dermatology , Skin Cancer Dermatology Market Report , Market Study , Market Trends , Forecasts Customized Intelligence , ஒன்றுபட்டது மாநிலங்களில் , தெற்கு கொரியா , ஒன்றுபட்டது கிஂக்டம் , வாழ்க்கை அறிவியல் , பாரத் நூல் பணியகம் , பாரத் நூல் பணியகம் வழங்குகிறது , பிரபலமாக உள்ளது சந்தை ஆராய்ச்சி அறிக்கை , தோல் புற்றுநோய் தோல் நோய் சந்தை ஆராய்ச்சி அறிக்கை , தோல் புற்றுநோய் தோல் நோய் சந்தை தோல் மருத்துவர்கள் ,

Acute itching in eczema patients linked to environmental allergens

New research from Washington University School of Medicine in St. Louis indicates that allergens in the environment often are to blame for episodes of acute itch in eczema patients, and that the itching often doesn t respond to antihistamines because the itch signals are being carried to the brain along a previously unrecognized pathway that current drugs don t target. ....

United States , Brians Kim , School Of Medicine , National Institute Of Allergy , Doris Duke Charitable Foundation , National Institute Of Arthritis , Washington University School Of Medicine , American Skin Association , Washington University School , National Institute , Skin Diseases , Infectious Diseases , National Institutes , University School , Louis Children , Medicine Health , Immunology Allergies Asthma , ஒன்றுபட்டது மாநிலங்களில் , பிரையன்ஸ் கிம் , பள்ளி ஆஃப் மருந்து , தேசிய நிறுவனம் ஆஃப் ஒவ்வாமை , டோரிஸ் டியூக் தொண்டு அடித்தளம் , தேசிய நிறுவனம் ஆஃப் கீல்வாதம் , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி ஆஃப் மருந்து , அமெரிக்கன் தோல் சங்கம் , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி ,

Scaling, splitting, irritating: Local dermatologist on winter dry skin, treatment & when to see a doctor

Scaling, splitting, irritating: Local dermatologist on winter dry skin, treatment & when to see a doctor
and last updated 2021-01-13 07:58:45-05
Scaling, splitting and irritating pain. For many, dry skin is an old enemy that always makes its return, especially during the winter months.
Dr. Valerie Harvey, a dermatologist with TPMG Hampton Roads Center for Dermatology, says it s a common problem for many of her clients right now.
Dry skin is a frequent complaint that I see in my clinic, said Dr. Harvey. It s cold outside, everyone has their heat on, hence the dryness in the air.
But, she says, there are ways to fight it. Her advice? ....

Valerie Harvey , Roads Center , வலேரி ஹார்வி , சாலைகள் மையம் , தோல் நோய் ,

Scientists discover key enzyme responsible for skin blistering in the elderly

The Granzyme B (GzmB) enzyme, which accumulates in certain tissues as we age, has been identified as a driver of itchy and sometimes life-threatening autoimmune conditions known as pemphigoid diseases (PDs), which cause blistering and skin erosion below the skin s surface. New research led by University of British Columbia (UBC) and Vancouver Coastal Health Research Institute (VCHRI) scientists has found that a gel containing a specific and potent inhibitor of GzmB activity, VTI-1002, resulted in significant improvements on skin affected by PDs. ....

United Kingdom , David Granville , Granzymeb Gzm , Nature Communications , Vancouver Coastal Health Research Institute , University Of British Columbia , British Columbia , Granzymeb Blocking , Medicine Health , ஒன்றுபட்டது கிஂக்டம் , டேவிட் கிரான்வில்லே , இயற்கை தகவல்தொடர்புகள் , வான்கூவர் கடலோர ஆரோக்கியம் ஆராய்ச்சி நிறுவனம் , பல்கலைக்கழகம் ஆஃப் பிரிட்டிஷ் கொலம்பியா , பிரிட்டிஷ் கொலம்பியா , மருந்து ஆரோக்கியம் , தோல் நோய் ,