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Frontiers | Predicting Spike Features of Hodgkin-Huxley-Type Neurons With Simple Artificial Neural Network

Hodgkin-Huxley (HH) -type model is the most famous computational model for simulating neural activity. It shows the highest accuracy in capturing neuronal spikes, and its model parameters have definite physiological meanings. However, HH-type models are computationally expensive. To address this problem, a previous study proposed a spike prediction module (SPM) to predict whether a spike will take place 1 ms later based on three voltage values with intervals of 1ms. Although SPM does well, it fails to evaluate the informative features of the spike. In this study, the feature prediction module (FPM) based on simple ANN was proposed to predict spike features including maximum voltage, minimum voltage, and dropping interval. Nine different HH-type models were adopted whose firing patterns cover most of the firing behaviors observed in the brain. Voltage and spike feature samples under constant external input current were collected for training and testing. Experiment results illustrated t ....

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Frontiers | Early Quaternary Tectonic Transformation of the Helan Shan: Constraints Due To Quantitative Geomorphology

The Helan Shan is located on the front edge of the expanding Tibetan Plateau. However, how the topography here responds to this propagation and its precise time constraints remains unknown. Based on the response process of fluvial landforms and tectonic evolution, we conducted a quantitative landform analysis of the Helan Shan region. Here, the spatial distribution features of various geomorphic indices were coupled, demonstrating that the mountain is tilting toward the west and north. The steeper downstream and gentle upper reaches indicate that the fluvial landforms have experienced an accelerated incision event, which can be attributed to the tectonic activity along the East Helan Shan Fault. Furthermore, the response time of the tectonic knickpoints ranges from 0.1¬–1.4 Ma based on the paleochannel reconstruction method. Combined with previous studies on low temperature thermochronology and active tectonics, we propose a tectonic transformation model where the Helan Shan shi ....

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Monetary incentives and peer referral in promoting secondary distribution of HIV self-testing among men who have sex with men in China: A randomized controlled trial

Yi Zhou and colleagues investigate whether monetary incentives and peer referral could improve a secondary distribution program for HIV self-testing among men who have sex with men in China. ....

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Mysterious Transition in Layered Compound Could Be Useful for Advanced Electrical Switches and Nonvolatile Memory

Many materials experience a phase transition, such as a metal to a superconductor, or liquid water to ice when there is a change in temperature. ....

United States , Hong Kong , Baiqing Lyu , Alex Smith , Xinyue Lu , Russian Academy Of Sciences , Us Department Of Energy , Moscow Institute Of Physics , University Of Leipzig , Us Army Research Office , Argonne National Laboratory , Hong Kong University Of Science , National Accelerator Laboratory , Gedik Lab , National Natural Science Foundation Of China , Shanghai Advanced Research Institute , Cornell University , Development Program Of China , Chinese Academy Of Sciences , Clemson University , Betty Moore Foundation , Songshan Lake Materials Laboratory , Miller Institute , National Key Research , University Of California At Berkeley , Stanford University ,

Scientists discover a mysterious transition in an electronic crystal

A research team led by MIT Professor Nuh Gedik discovered an unusual transition in a layered compound called EuTe4. ....

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