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CNN This Morning Weekend

bleeding. cohen says these types of side effects were mostly mild in the trial. >> we do know that this has a low ratde of causing macro hemorrhage, a low rate less than 1%. >> in the phase 3 clinical trial there were seven deaths in the placebo group and six in the drug group. according to investigators though, none of the drugs were said to be due to the drug or aria. the new england journal of i had medicine published an additional death of a patient who had been given blood thinners. >> it's difficult to say it was the drug when another drug can cause significant bleeding. >> reporter: they agree while this drug shows promise, it must come with caution. for example, avoiding blood thinners while taking the medication. >> i will prescribe this drug in

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The Lead With Jake Tapper

hemorrhage, not necessarily fatal, but a low rate, less than 1%. >> reporter: in the phase 3 clinical trial, there were seven deaths in the placebo cgroup an six in the drug group. none were considered to be due to lecanemab. the new england journal of medicine recently published details of a death of a patient on the drug that had been given blood thinners. >> it's pretty hard to say lecanemab caused that when you're giving a drug that could cause significant bleeding. however, the combination gives us pause. >> reporter: neurologist dr. richard isaacson agrees that while this drug shows promise, it must come with caution. for example, avoiding blood thinners while taking the medication. >> i will prescribe this drug in the right person at the right dose and in a very carefully monitored way. but this drug is not for everyone. >> reporter: for jack, the possibility of continuing to live a full life, spending quality time with all four

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Anderson Cooper 360

death rates about the same in both groups. but it's going to end up being a discussion with the doctor, the patient, and the family if this gets approved and to really weigh those risk benefits. it may not be applicable to people on blood thinners. >> so, what's the process now? >> so, i mean, at this point, i think if it gets approved, so, the drug company is hoping that it will get accelerated approval in january and they will apply for full approval by april. then the big question is what happens when you roll it out in the real world. does that one point difference translate to something meaningful for families. it may. giving somebody one more month, two more months, those are precious time periods where a person can function, where you can be with them, where they can recognize you. we're also going to have to see what happens in the real world. those patients in the real world are different than those in the real world. it may be costly. with aduhelm, that was about

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CNN Newsroom

senior medical correspondent elizabeth cohen joins us now. how promising is this new drug? and given the side effects, is it worth it in terms of what researchers are saying at this point? >> bianna, essentially that's what the u.s. food & drug administration has to decide. they fasttracked this drug, but the study authors themselves say that longer studies need to be done. so efficacy, first, what they did, they took 1800 people between the ages of 50 and 90 who had mild early stages of alzheimer's. hat goff a ploo seo, hat the dripping. the half that got the drug did see a decline, but 27% slower. also, the folks in the drug group they lower levels of amyloid.

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New Day With John Berman and Brianna Keilar-20211125-11:49:00

nobody who got the pill died. seven agents in the placebo group. zero in the drug group. here's the but. they have to be taken very early in the course of infection. that's why testing is so important. in the clinical trials, they got those results because people who took pfizer took them within three days of symptom onset. they felt sick and within three days they took the pill. for merck, it was within five days of symptom onset. so that means you need to know pretty quickly whether you have covid. it needs to be accessible, affordable, and the results need to come back quickly. a few months ago i had a test where i got the results back 10 days later. not helpful. and i have heard stories from many, many people that i know. it's very crucial that testing be improved. when the fda advisers sit down

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Special Report With Bret Baier-20211018-22:14:00

factors they are being advised to get the booster shot. are their other things? i know merck is working on this pill. are there other treatments that are on the way that could have somehow made a difference? >> well, there may be, bret, a drug was tested in high risk individuals. and it was found to cut deaths from covid to zero. it was a six deaths in the placebo group zero in the drug group. many have suggested that it would be useful on a congress pam that the use basis right now. like president trump got monoclonal. antidepressant reduce inflammation. steroid nebulizers and either hyper tonic saline sprays. these are all vaccine therapeutics. we put a lot of focus on vaccines but it turns out these other things may also be valuable. >> bret: dr. makary, we

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