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New drug candidate reverses obesity in mice by transforming liver metabolism

A mitochondrial transcription inhibitor (IMT) shifted metabolism in high-fat diet mice toward fatty acid oxidation, leading to weight loss, reduced liver fat, and improved glucose tolerance.

Lab-animal-monitoring-system , Nature-metabolism , Comprehensive-lab-animal-monitoring-system , Taolin-yuan , Postdoctoral-researcher , Professor-nils-g , Principal-investigator , Liver , Etabolism , Besity , Dipose

Columbia researchers uncover brain's ability to control inflammation

The brain can direct the immune system to an unexpected degree, capable of detecting, ramping up and tamping down inflammation, shows a new study in mice from researchers at Columbia's Zuckerman Institute.

United-states , Mengtong-li , Eric-jeong , Zhao-jin , Cajal-neurosciences , Felipe-castro-martinez , Charless-zuker , Columbia-vagelos-college-of-physicians , Autoimmune-association , Columbia-university , National-institute-of-allergy , Howard-hughes-medical-institute

Bay Area real estate portfolio is bought for well over $100 million

A big Bay Area portfolio of office, commercial and industrial buildings has been bought by a New York-based real estate investment group in a deal valued at well over $100 million.

New-york , United-states , Santa-clara-county-recorder-office , Cadillac-court , Bay-area , New-york-based , San-jose , Santa-clara-county-recorder , Google-maps , King-road , South-bay

Research identifies a unique protein fingerprint linked to very short sleep and increased diabetes risk

Study highlights the association between sleep duration and proteomic fingerprints, finding that very short sleep is linked to proteins involved in inflammation and cell death that increase the risk of diabetes mellitus (DM) but not coronary heart disease (CHD).

Osklo-studio , Diabetes , Eart , Eart-disease , Leep , Ardiovascular-disease , Ell , Ell-death , Oronary-heart-disease , Iabetes-mellitus , Nflammation

Sphere Fluidics appoints Dale Levitzke as Chief Executive Officer

Sphere Fluidics, a leading provider of innovative microfluidics-based solutions for single-cell analysis and isolation, today announced the appointment of Dale Levitzke as CEO with immediate effect,...

Melbourne , Victoria , Australia , Frankf-craig , Chris-abell , Dale-levitzke , Wilhelm-huck , Illumina-inc , Trobe-university , Helixis-inc , Dropworks-inc , From-sphere-fluidicsmay

iTWire - Ip.Glass achieves eight specialisations through Fortinet Engage Partner Program

COMPANY NEWS: Ip.Glass is the first Australian partner to successfully attain specialisations in all eight categories offered by the Fortinet Engage P...

Australia , Australian , John-milionis , Semyon-taskin , Ip-glas , Fortinet-engage-partner-program , Fortinet-engage-partner , Fortinet-security-fabric , Engage-partner-program , Technology-news , Ech-news , Echnology-trends

Study uncovers molecular mechanism linking nonsense-mediated RNA decay to microcephaly

Nonsense-mediated RNA decay, or NMD, is an evolutionarily conserved molecular mechanism in which potentially defective messenger RNAs, or mRNAs (genetic material that instructs the body on how to make proteins), are degraded.

University-of-southern-california , California , United-states , Liang-chen , Chun-wei-chen , National-institutes-of-health , School-of-medicine , University-of-california , California-institute-of-regenerative-medicine , Sika-zheng , National-institutes , California-institute

First FDA-approved cellular therapy for metastatic melanoma available in South Florida

Patients in South Florida with metastatic melanoma will soon have access to the first cellular therapy for this advanced form of skin cancer, following its recent approval by the Food and Drug Administration (FDA).

Miami , Florida , United-states , Iovance-biotherapeutics , Jose-lutzky , Centers-for-disease , University-of-miami-miller-school-medicine , Drug-administration , Sylvester-comprehensive-cancer-center , Cutaneous-oncology-services-at-sylvester , Miami-miller-school , South-florida