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Ciliopathies: A new understanding of the role of the NSL complex

The non-specific lethal (NSL) complex is a chromatin-associated factor that has been shown to regulate the expression of thousands of genes in both fruit flies and mammals. ....

Tsz Hong Tsang , Megan Craig , Max Planck , Asifa Akhtar , Max Planck Institute In Freiburg , Science Advances , Hong Tsang , Max Planck Institute , Tsz Hong , Hearing Loss , Kidney Disease , Visual Impairment ,

Study connects neural gene expression differences to functional distinctions

The Picower Institute for Learning and Memory found that the two closely related neuronal subtypes differed from each other in how they expressed more than 800 genes. By manipulating genes whose expression differed most prominently, the scientists were then able to show how they produced several of the observable differences between the cells. ....

Charles Whittaker , Nicole Aponte , Troy Littleton , Karen Cunningham , Yulia Akbergenova , Suresh Jetti , National Institutes Of Health , Picower Institute For , Cognitive Sciences , Picower Institute , Menicon Professor , Andres Crane , Nicole Aponte Santiago , National Institutes , Picower Institute For Learning And Memory , Ene Expression , Troy Littleton , Suresh Jetti , Hasic Neurons , Onic Neurons , Ctive Zones Azs , Soform Patchseq ,