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Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2 Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2, preventing expression of genes that encode proteins in cells such as resident macrophages in the nose and pulmonary alveoli, and epithelial cells lining the alveoli, all of which are entry points for the virus. The hormone, therefore, prevents infection of these cells by the virus and inhibits the immune response so that the virus remains in the respiratory tract for a few days, eventually leaving to find another host. The discovery by researchers at...

Researchers at the Francis Crick Institute, the UCL Cancer Institute, and the Cancer Research UK Lung Cancer Centre of Excellence have identified genetic changes in tumors which could be used to predict if immunotherapy drugs would be effective in individual patients.

New partnership to develop test for predicting disease course in pediatric Crohn's patients The Crohn's & Colitis Foundation, the leading non-profit organization focused on both research and patient support for inflammatory bowel disease (IBD), has entered into a partnership with LifeArc, an independent medical research charity that advances translation of early science into health care treatments or diagnostics, to potentially develop the first clinical lab test to predict disease course in pediatric patients with Crohn's disease and response to treatment. A prognostic test which could accur...

Tue, 01/26/2021 LAWRENCE — This spring, 41 KU students will receive an Undergraduate Research Award. UGRA recipients are awarded a $1,000 scholarship as they work on mentored research and creative projects.   Students apply for UGRAs by writing a four-page research proposal under the guidance of a mentor. Faculty reviewers evaluate the applications based on the merit of the applicant's proposal and a recommendation from the mentor.   “Undergraduate research allows students to apply their classroom knowledge to real-world problems, and experiential learning opportunities like ...

New Method Helps Design Treatments For Deadly Cancers – Gliomas by Karishma Abhishek on  January 23, 2021 at 2:21 PM New method termed as transcriptomic profile (the number of copies of each gene in a cell) of the tumor helps recognize some of the most serious forms of the tumors - Gliomas as per the scientists at Medical College of Georgia reported in the journal Scientific Reports. Gliomas are the common type of brain tumor in adults that affects the support cells of neurons - glial cells. Three subtypes of gliomas range from the generally more treatable astrocytoma...