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Altering a mosquito's gut genes shows promise to curb malaria


Altering a mosquito s gut genes shows promise to curb malaria
Altering a mosquito s gut genes to make them spread antimalarial genes to the next generation of their species shows promise as an approach to curb malaria, suggests a preliminary study published today in
eLife.
The study is the latest in a series of steps toward using CRISPR-Cas9 gene-editing technology to make changes in mosquito genes that could reduce their ability to spread malaria. If further studies support this approach, it could provide a new way to reduce illnesses and deaths caused by malaria.
Growing mosquito resistance to pesticides, as well as malaria parasite resistance to antimalarial drugs, has created an urgent need for new ways to fight the disease. Gene drives are being tested as a new approach. They work by creating genetically modified mosquitoes that, when released into the environment, would spread genes that either reduce mosquito populations or make the insects less likely to s ....

United Kingdom , City Of , Astrid Hoermann , Nikolai Windbichler , Emily Henderson , Research Associate At Imperial College London , Imperial College London , Department Of Life Sciences , First Author , Research Associate , Senior Lecturer , Life Sciences , Imperial College , Gene Editing , Next Generation , ஒன்றுபட்டது கிஂக்டம் , நகரம் ஆஃப் , எமிலி ஹென்டர்சன் , ஆராய்ச்சி இணை இல் ஏகாதிபத்தியம் கல்லூரி லண்டன் , ஏகாதிபத்தியம் கல்லூரி லண்டன் , துறை ஆஃப் வாழ்க்கை அறிவியல் , முதல் நூலாசிரியர் , ஆராய்ச்சி இணை , மூத்தவர் விரிவுரையாளர் , வாழ்க்கை அறிவியல் , ஏகாதிபத்தியம் கல்லூரி ,

Residents in majority-Black neighborhoods experience higher rates of severe maternal morbidity


Residents in majority-Black neighborhoods experience higher rates of severe maternal morbidity
Residents in majority-Black neighborhoods experience higher rates of severe pregnancy-related health problems than those living in predominantly-white areas, according to a new study of pregnancies at a Philadelphia-based health system, which was led by researchers in the Perelman School of Medicine at the University of Pennsylvania. The findings, published today in
Obstetrics and Gynecology, suggest that neighborhood-level public health interventions may be necessary in order to lower the rates of severe maternal morbidity such as a heart attack, heart failure, eclampsia, or hysterectomy and mortality in the United States. ....

United States , University Of Pennsylvania , Pennsylvania Hospital , Chester County , Mary Regina Boland , Jessicar Meeker , Elisa Levine , Emily Henderson , Centers For Disease , Hospital Of The University Pennsylvania , Us Census Bureau , University Of Pennsylvania Health System , Perelman School Of Medicine , Perelman School , Pennsylvania Health System , Disease Control , Penn Medicine , Health System , Penn Presbyterian Hospital , Chester County Hospital , Open Data Philly , Regina Boland , Heart Attack , Heart Failure , Maternal Health , Public Health ,

Non-invasive neuromodulation approaches can prevent invasive surgery in Parkinson's patients


Non-invasive neuromodulation approaches can prevent invasive surgery in Parkinson s patients
From optogenetics to sonogenetics to magnetognetics, scientists around the world are investigating new techniques to treat Parkinson s disease without the need for invasive surgery.
There is still no treatment that can reverse the effects of Parkinson s disease, a condition estimated to affect 10 million people worldwide. As life expectancy increases, the number of people suffering from this disease is set to rise in the future, making the need for effective treatment a priority.
Doctors prescribe oral medication to alleviate the main symptoms and, for a few patients, use deep brain stimulation. The electrodes stimulate the affected areas and relieve the reactions induced by the disease such as tremor or rigidity. ....

Sebastian Neumann , Rolf Heumann , Fabian Raudzus , Sreekanth Chalasani , Emily Henderson , Salk Institute For Biological , University Ruhr Bochum , Kyoto University , Stanford University , Associate Professor , Salk Institute , Biological Studies , Brain Stimulation , Deep Brain Stimulation , Life Expectancy , Opto Genetics , Parkinson 39s Disease , செபாஸ்டியன் நியூமன் , ரோல்ஃப் மனித , ஸ்ரீகாந்த் சலசனி , எமிலி ஹென்டர்சன் , சாள்க் நிறுவனம் க்கு உயிரியல் , கியோட்டோ பல்கலைக்கழகம் , ஸ்டான்போர்ட் பல்கலைக்கழகம் , இணை ப்ரொஃபெஸர் , சாள்க் நிறுவனம் ,

Children less likely to spread SARS-CoV-2 than adults


Children less likely to spread SARS-CoV-2 than adults
A study conducted by researchers in Canada suggests that children may be less likely than adults to spread the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19).
As recently reported in
The Canadian Medical Association Journal (CMAJ), the study found that samples taken from 175 children aged 17 years or younger were about half as likely to contain culturable viruses than samples taken from adults.
Furthermore, when SARS-CoV-2 was successfully cultured, a significantly less viable virus was present in samples from children than from adults.
The team from Cadham Provincial Laboratory in Winnipeg, Manitoba, says the findings suggest that children do not appear to be the main drivers of SARS-CoV-2 transmission, which has important public health and clinical implications. ....

Jared Bullard , Sally Robertson , Cadham Provincial Laboratory In Winnipeg , Canadian Medical Association Journal , Cadham Provincial Laboratory , Sars Cov 2 , Corona Virus , Coronavirus Disease Covid 19 , Polymerase Chain Reaction , Public Health , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , ஜாரெட் புல்லார்ட் , சாலி ராபர்ட்சன் , கனடியன் மருத்துவ சங்கம் இதழ் , கொரோனா வைரஸ் , பொது ஆரோக்கியம் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,