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FDA alerts health care providers and clinical laboratory staff about SARS-CoV-2 viral mutation

The U.S. Food and Drug Administration is alerting clinical laboratory staff and health care providers that the FDA is monitoring the potential impact of viral mutations, including an emerging variant from the United Kingdom known as the B.1.1.7 variant, on authorized SARS-CoV-2 molecular tests, and that false negative results can occur with any molecular test for the detection of SARS-CoV-2 if a mutation occurs in the part of the virus's genome assessed by that test. ....

United Kingdom , Emily Henderson , Drug Administration , Health Care , Sars Cov 2 , ஒன்றுபட்டது கிஂக்டம் , எமிலி ஹென்டர்சன் , ஆரோக்கியம் பராமரிப்பு ,

Gene therapy can effectively treat mice with tuberous sclerosis complex, shows study

Gene therapy can effectively treat mice with tuberous sclerosis complex, shows study
Patients with tuberous sclerosis complex, a genetic disorder characterized by the growth of noncancerous tumors in multiple organs of the body, have limited treatment options. A team led by investigators at Massachusetts General Hospital (MGH) has now shown that gene therapy can effectively treat mice that express one of the mutated genes that cause the disease. The research is published in
Science Advances.
The gene, called TSC2, codes for tuberin, a protein that acts to inhibit cell growth and proliferation. When mutations occur in TSC2, resulting in a lack of tuberin in cells, the cells enlarge and multiply, leading to the formation of tumors. ....

United States , Shilpa Prabhakar , Emily Henderson , Drug Administration , Massachusetts General Hospital , Co Lead Author , Gene Therapy , Mouse Model , Genetic Disorder , Medical School , Tuberous Sclerosis , ஒன்றுபட்டது மாநிலங்களில் , ஷில்பா ப்ர்யாப்‌ஹகர் , எமிலி ஹென்டர்சன் , மாசசூசெட்ஸ் ஜநரல் மருத்துவமனை , இணை வழி நடத்து நூலாசிரியர் , கீந் சிகிச்சை , சுட்டி மாதிரி , ஜெநெடிக் கோளாறு , மருத்துவ பள்ளி , கிழங்கு ஸ்க்லரோசிஸ் ,

Researchers unravel the process that makes viruses infectious

Researchers unravel the process that makes viruses infectious
Researchers have for the first time identified the way viruses like the poliovirus and the common cold virus package up their genetic code, allowing them to infect cells.
The findings, published today (Friday, 8 January) in the journal
PLOS Pathogens by a team from the Universities of Leeds and York, open up the possibility that drugs or anti-viral agents can be developed that would stop such infections.
Once a cell is infected, a virus needs to spread its genetic material to other cells. This is a complex process involving the creation of what are known as virions - newly-formed infectious copies of the virus. Each virion is a protein shell containing a complete copy of the virus s genetic code. The virions can then infect other cells and cause disease. ....

Peter Stockley , Reidun Twarock , Emily Henderson , Astbury Biostructure Laboratory , World Health Organization , University Of Leeds , Astbury Centre , Structural Molecular Biology , Professor Reidun Twarock , World Health , Common Cold , பீட்டர் ஸ்டாக்லீ , எமிலி ஹென்டர்சன் , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , பல்கலைக்கழகம் ஆஃப் லீட்ஸ் , கட்டமைப்பு மூலக்கூறு உயிரியல் , உலகம் ஆரோக்கியம் , பொதுவானது குளிர் , எதிர் மின்னணு ,

J'pura University begins research on corona strain variations in the country

Saturday, 09 January 2021 - 11:51
The Institute of Allergy Immunology and Cell Biology at the University of Sri Jayewardenepura has already commenced genetic analysis research to determine whether variations in the viral variations have occurred of coronavirus infections reported in Sri Lanka.
Director of the institute Dr. Chandima Jeewandara stated that the relevant research is being carried out using biological samples provided to the institute for PCR testing and samples sent by the Ministry of Health.
The Institute of Allergy Immunology and Cell Biology, University of Sri Jayewardenepura has been conducting PCR tests since March and around 80,000 tests have been carried out so far. ....

Sri Lanka , Donald Trump , Nancy Pelosi , House Speaker Nancy Pelosi , President Donald Trump , Killinochchi Hospital , Medi Cal , Corona Virus , ஸ்ரீ லங்கா , டொனால்ட் துருப்பு , நான்சி பெளோஸி , வீடு பேச்சாளர் நான்சி பெளோஸி , ப்ரெஸிடெஂட் டொனால்ட் துருப்பு , செய்தித் தொடர்பாளர் , மேதி கலோரி , கொரோனா வைரஸ் , நோய்த்தொற்றுக்கு உள்ளானவர் ,

RNA sequencing data reveals three major molecular subtypes of Alzheimer's disease

RNA sequencing data reveals three major molecular subtypes of Alzheimer s disease
Researchers at the Icahn School of Medicine at Mount Sinai have identified three major molecular subtypes of Alzheimer s disease (AD) using data from RNA sequencing. The study advances our understanding of the mechanisms of AD and could pave the way for developing novel, personalized therapeutics.
The work was funded by the National Institute on Aging, part of the National Institutes of Health (NIH), and published in
Science Advances on January 6, 2021.
RNA is a genetic molecule similar to DNA that encodes the instructions for making proteins. RNA sequencing is a technology that reveals the presence and quantity of RNA in a biological sample such as a brain slice. ....

Emily Henderson , Icahn School Of Medicine At Mount Sinai , National Institutes Of Health , Genomic Sciences , National Institute On , Medicines Partnership , Icahn School Of Medicine , National Institute On Aging , Icahn School , Mount Sinai , National Institute , National Institutes , Science Advances , Bin Zhang , Transformative Disease Modeling , Accelerating Medicines Partnership , Target Discovery , Preclinical Validation , Alzheimer 39s Disease , Immune Response , Irna Sequencing , எமிலி ஹென்டர்சன் , இக்ஹ்ன் பள்ளி ஆஃப் மருந்து இல் ஏற்ற சினை , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , தேசிய நிறுவனம் ஆன் , மருந்துகள் கூட்டு ,