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Emerging protein-based immunotherapies could lead to highly effective cancer treatments


Emerging protein-based immunotherapies could lead to highly effective cancer treatments
In a new commentary for the journal
Science, an associate vice president for research at The University of Texas at Arlington argues that emerging protein-based immunotherapies could lead to highly effective off-the-shelf cancer treatments for more patients.
Jon Weidanz, who also is a professor in the College of Nursing and Health Innovation at UTA, is the author of a perspective regarding the development of cancer immunotherapies.
His article, Targeting cancer with bispecific antibodies, will appear in the March 5 edition of
Science. It evaluates the findings of three studies by researchers at Johns Hopkins University and proposes that an emerging method of protein-based immunotherapy that targets commonly occurring mutations in cancer cells or neoantigens mutated antigens produced by tumor cells could lead to treatments that are effective for oncology patients. ....

United States , James Grover , Jon Weidanz , Emily Henderson , Johns Hopkins University , College Of Nursing , Health Innovation , University Of Texas At Arlington , Immune System , T Cell , ஒன்றுபட்டது மாநிலங்களில் , ஜேம்ஸ் தோப்பு , எமிலி ஹென்டர்சன் , ஜான்ஸ் ஹாப்கின்ஸ் பல்கலைக்கழகம் , கல்லூரி ஆஃப் நர்சிங் , ஆரோக்கியம் கண்டுபிடிப்பு , பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் இல் ஆர்லிங்டன் , நோயெதிர்ப்பு சிகிச்சை , நோய் எதிர்ப்பு சக்தி அமைப்பு , டி செல் ,

Study discovers similarities between the genetic bases of various eating disorders


Study discovers similarities between the genetic bases of various eating disorders
Anorexia nervosa, bulimia nervosa and binge-eating disorder are the three main eating disorders that 4 out of in 10 individuals living in Western Europe will experience at some point in their lives.  In recent years, studies on the genetic basis of anorexia nervosa have highlighted the existence of predisposing genetic markers, which are shared with other psychiatric disorders.
By analyzing the genome of tens of thousands of British people, a team from the University of Geneva (UNIGE), the University Hospitals of Geneva (HUG), King s College London, the University College London, the University of North Carolina (UNC) and The Icahn School of Medicine at Mount Sinai have built on these initial results by discovering similarities between the genetic bases of these various eating disorders, and those of other psychiatric disorders. ....

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Diverse patient population helps identify gene variant associated with childhood asthma


Diverse patient population helps identify gene variant associated with childhood asthma
Researchers at Henry Ford Health System, as part of a national asthma collaborative, have identified a gene variant associated with childhood asthma that underscores the importance of including diverse patient populations in research studies.
The study is published in the print version of the
American Journal of Respiratory and Critical Care Medicine.
For 14 years researchers have known that a casual variant for early onset asthma resides on chromosome 17, which holds one of the most highly replicated and significant genetic associations with asthma. Henry Ford researchers acknowledged they would not have identified it in this study without a diverse patient population that included African Americans, many from the metro Detroit area. ....

United States , Hakon Hakonarson , Esteban Burchard , L Keoki Williams , Henry Ford , Emily Henderson , National Center , National Heart Lung , Genomic Medicine Research , Harvard Medical School , Blood Institute Trans , Henry Ford Health System , University Of California San Francisco , Researchers At Henry Ford Health System , Health Statistics , American Journal , Critical Care , African American , Keoki Williams , Study Senior Author , Henry Ford Health , Henry Ford Led , California San Francisco , Asthma Translational Genomics Collaborative , Blood Institute , Precision Medicine ,