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Researchers expand understanding of hop genome with implications for brewing industry

Oregon State University and U.S. Department of Agriculture researchers have significantly expanded the understanding of the hop genome, a development with important implications for the brewing industry and scientists who study the potential medical benefits of hops. ....

United States , Oregon State University , John Henning , David Hendrix , Pacific Biosciences , Emily Henderson , Us Department Of Agriculture , Oregon State College Of Agricultural Sciences , Department Of Biochemistry , Agricultural Research Service , Study Co , School Of Electrical Engineering , State University , Electrical Engineering , Computer Science , Oregon State College , Agricultural Sciences , Study Co Corresponding Author , Hop Geneticist , Oregon State , Research Service , ஒன்றுபட்டது மாநிலங்களில் , ஓரிகந் நிலை பல்கலைக்கழகம் , ஜான் கோழி , டேவிட் ஹென்ட்ரிக்ஸ் , பெஸிஃபிக் உயிர் அறிவியல் ,

Study shows how m6A regulators influence metabolic heterogeneity of hepatocellular carcinoma

Study shows how m6A regulators influence metabolic heterogeneity of hepatocellular carcinoma
Cancer cells acquire growth advantages over normal cells in myriad ways. Changes in cell programming allow these cells to grow in an uncontrolled fashion, thereby forming the cancer mass.
Hepatocellular carcinoma (HCC), being highly malignant and invasive with a high recurrence rate and drug-resistant phenotype, is one of the most dreadful cancers. Understanding the underlying molecular mechanisms is crucial to design therapeutic interventions and to predict patient prognosis.
Cancer cells use metabolic, immunogenic, or growth-related strategies, which can be controlled by a number of alterations in the cell process. Of these, post-transcriptional RNA modification has recently sparked interest among cancer biologists. N6-methyladenosine (m6A) methylation, a type of RNA modification, remains the most abundant epigenetic (non-DNA related) modification in eukaryotic cells. ....

Lun Xiu Qin , Emily Henderson , Fudan University , International Cancer Genome Consortium , Cancer Biology , Cancer Genome Atlas , Hepatocellular Carcinoma , Liver Cancer , லூந் க்ஷிு குயின் , எமிலி ஹென்டர்சன் , சர்வதேச புற்றுநோய் மரபணு கூட்டமைப்பு , புற்றுநோய் உயிரியல் , புற்றுநோய் மரபணு அட்லஸ் , வளர்சிதை மாற்றம் , கல்லீரல் புற்றுநோய் , அறுவை சிகிச்சை ,

Could rotavirus vaccine platforms aid in the immunization campaign against SARS-CoV-2?

Could rotavirus vaccine platforms aid in the immunization campaign against SARS-CoV-2?
Rotavirus is a common diarrheal disease that affects young children. Live oral rotavirus vaccines have been used to reduce its incidence in many countries. However, with the onset of the coronavirus disease 2019 (COVID-19) pandemic, and amid focus on vaccines as the only definitive method of durable control, a new study describes the possibility of producing a combined vaccine against both infections.
The study began with the generation of recombinant (r)SA11 rotaviruses, into which segment 7 modified RNAs were introduced. These encoded sequences for the non-structural protein NSP3 and some parts of the viral spike. ....

Liji Thomas , Indiana University , Expression Platform , Image Credit , Coronavirus Disease Covid 19 , Sars Cov 2 , Corona Virus , Spike Protein , Structural Protein , இந்தியானா பல்கலைக்கழகம் , வெளிப்பாடு நடைமேடை , படம் கடன் , கொரோனா வைரஸ் , சர்வதேச பரவல் , ஸ்பைக் ப்ரோடீந் , கட்டமைப்பு ப்ரோடீந் ,

More diverse SARS-CoV-2 variants identified within infected children than in adults

More diverse SARS-CoV-2 variants identified within infected children than in adults
As the severe acute respiratory coronavirus 2 (SARS-CoV-2) infections spread rapidly over the world, causing the ongoing pandemic of coronavirus disease 2019 (COVID-19), transmission patterns have evolved quickly. At first, most infections appeared to have been imported, but by the end of February 2020, community spread was occurring in a sustained manner.
A new preprint on the
medRxiv server describes the identification of multiple circulating variants of SARS-CoV-2 during this early pandemic period from Asia and Europe. In addition, there were multiple local introductions of different variants, that resulted in multiple waves of transmission. ....

New York , United States , District Of Columbia , New Jersey , Liji Thomas , Global Initiative For Sharing All Influenza Data , Global Initiative , Sharing All Influenza Data , New York State , Coronavirus Disease Covid 19 , Genomic Sequencing , Sars Cov 2 , Corona Virus , Severe Acute Respiratory , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , மாவட்டம் ஆஃப் கொலம்பியா , புதியது ஜெர்சி , உலகளாவிய முயற்சி , புதியது யார்க் நிலை , கொரோனா வைரஸ் , சர்வதேச பரவல் , கடுமையானது எடுப்போசை சுவாச ,

A different strategy for wastewater detection of SARS-CoV-2

Researchers tested a variety of RNA concentration and extraction methods and assays to develop a protocol for testing SARS-CoV-2 in wastewater, which may help improve COVID-19 surveillance. ....

Lakshmi Supriya , Maxwell Purefood , Phd Feb , Sars Cov 2 , Corona Virus , Coronavirus Disease Covid 19 , Infectious Diseases , Rna Extraction , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , லட்சுமி சுப்ரியா , ஃப்ட் ஃபெப் , கொரோனா வைரஸ் , தொற்று நோய்கள் , ர்ந பிரித்தெடுத்தல் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,