Mutation in Hailey-Hailey Disease
Analyzing pathogenic mechanism in Hailey-Hailey Disease patients by using cycloheximide chase assay, CCK8 assay and in silico modeling of SPCA1 mutant
Source: dovepress.com
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Probing SARS-CoV-2-positive plasma to identify potential factors correlating with mild COVID-19 in Ghana, West Africa | BMC Medicine
West Africa has recorded a relatively higher proportion of asymptomatic coronavirus disease 2019 (COVID-19) cases than the rest of the world, and West Africa-specific host factors could play a role in this discrepancy. Here, we assessed the association between COVID-19 severity among Ghanaians with their immune profiles and ABO blood groups. Plasma samples were obtained from Ghanaians PCR-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive individuals. The participants were categorized into symptomatic and asymptomatic cases. Cytokine profiling and antibody quantifi...
Source: biomedcentral.com
Mesoporous Silica Nanoparticles Aggravates Atopic Dermatitis
Examining the greater plasma protein adsorption on MSN leads to serious inflammatory reactions in (DFE)-induced mouse atopic dermatitis. Click to read more...
Source: dovepress.com
Cureus | Correlation of Breakthrough Infection During the Omicron Wave With Seropositivity of Vaccinated Patients Undergoing Hemodialysis
Background Patients with chronic kidney disease and undergoing hemodialysis are at greater risk of developing COVID-19. In spite of vaccine efficacy, SARS-CoV-2 breakthrough infection has been reported in several studies. This study was carried out to assess if seroconversion could predict SARS-CoV-2 breakthrough infection in a cohort of vaccinated patients undergoing hemodialysis. Methodology Patients undergoing maintenance hemodialysis for at least three months and who had received two doses of BBV152 or AZD1222 vaccine were included in the study. Their baseline IgG antibodies to SARS-CoV-2 ...
Source: cureus.com
Depression management and antiretroviral treatment outcome among people living with HIV in Northwest and East regions of Cameroon | BMC Infectious Diseases
Several interventions have shown benefits in improving mental health problems such as depression which is common in people living with HIV. However, there is a paucity of evidence on the effect of these interventions in improving HIV treatment outcomes. This study aimed at bridging this evidence gap and guiding the integration of depression and HIV management, particularly in rural health settings of Cameroon. We carried out a cluster-randomized intervention study targeting persons aged 13 years and above who had been on antiretroviral treatment for 6–9 months. Particip...
Source: biomedcentral.com