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Researchers are engineering ways to alter genes or swap flawed ones with healthy replacements, hoping to cure diseases or enable the body to better combat them.

Hideho Okada, MD, PhD, discusses cancer immunoprevention through the lens of vaccine approaches in patients with low-grade glioma.

The ideal therapy for a disease works exclusively at the site of the disease.But when it comes to the brain, which is wrapped in a protective barrier and contains thousands of different cell types, this ideal is very hard to achieve.Now, scientists a

T cells used in immunotherapy treatments can get exhausted and shut down by fighting cancer cells and tumors. Using a CRISPR-based edit on these cells’ genomes, researchers at UCSF and Gladstone Institutes have rendered the therapeutic cells more resilient against tumors.

Engineered Immune Cells Eliminate Brain Cancer in Mice Researchers developed a new CAR T-cell therapy that targets specific growth factor receptors in glioblastoma to eliminate brain tumors. Brooke Dulka, PhD May 25, 2021 In Australia’s oldest medical research institute, researchers work to cure an aggressive brain cancer known as glioblastoma. The last decade has transformed the field of cancer research; blood cancers that were once death sentences now have treatment options. But glioblastoma remains a deadly enigma.  “I realized there was hardly any research happening in brain cancer, ...