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'Planning for dropouts': Drugmakers grapple with testing unproven vaccines on seniors

TORONTO
At age 70, retired nurse Donna Lessard can expect to be towards the front of the line for a COVID-19 vaccine when supply and distribution expands in coming months.
But instead, she s opted for an unproven vaccine candidate she can have now a two-dose product by the Quebec City-based biopharmaceutical Medicago currently running Phase 2 clinical trials.
Because the trials are blinded, the Montrealer doesn t know if last month she received a second dose of the prospective vaccine or a placebo, and may not know for a year well after most Canadians are expected to receive one of several licensed vaccines. ....

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Coronavirus: Israel, a global leader in COVID-19 vaccinations, finds limits

TEL AVIV, ISRAEL
When it comes to fighting the coronavirus, Israel is discovering the limits of vaccines.
The country famous for its high-tech prowess and spirit of innovation is home to the world s speediest vaccination drive, fueled from the top by national pride and a deep longing to start getting back to life, as Prime Minister Benjamin Netanyahu put it.
But experts say reopening the country will still take months, complicated by coronavirus mutations that have spread from Britain and South Africa, a refusal among some sectors to adhere to safety rules and wobbles in the pace of vaccinations of people under 60. ....

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Coronavirus mutated in immunocompromised patient after plasma therapy: case study

A case study involving a patient in his 70s has raised the possibility that SARS-CoV-2, the virus that causes COVID-19, could evolve in immunocompromised individuals infected over an extended period of time and treated with convalescent plasma therapy, U.K. researchers say. ....

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Coronavirus: Rare 'COVID arm' phenomenon a harmless immune response to vaccination, experts say

Some recipients of the Moderna COVID-19 vaccine report having COVID arm, where a raised lesion or rash occurs after inoculation, but experts say the reaction is harmless. ....

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Coronavirus: Biden administration to deploy approximately 1,000 troops to assist with COVID-19 vaccination effort

The Biden administration announced Friday that it will deploy approximately 1,000 troops across the United States to assist with coronavirus vaccination efforts. ....

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