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Dr Ball on the Use of Luspatercept in MDS With Anemia

Somedeb Ball, MBBS, discusses the benefits of luspatercept for patients with anemia due to a myelodysplastic syndrome.

Department-of-medicine , Division-of-hematology-oncology , Vanderbilt-university-medical-center , Somedeb-ball , Hematology-oncology , Bbs , Luspatercept , Patients-with-anemia-due-toa-myelodysplastic-syndrome ,

European Commission Approves Frontline Luspatercept for Transfusion-Dependent Anemia in Lower-Risk MDS

The European Commission has expanded its approval of luspatercept to include frontline treatment of transfusion-dependent anemia due to lower-risk MDS.

Japan , Bristol-myers-squibb , Monica-shaw , European-commission , European-union , European-markets , Mds , Luspatercept , The-european-commission ,

Emerging Clinical Trials in MDS and Key Takeaways from ASH 2023

The panel discusses emerging clinical trials in the MDS treatment space and offers key takeaways from the 2023 ASH Annual Meeting.

Evolving-treatment-landscape , Myelodysplastic-syndromes , Clinical-trials , Key-takeaways , Mds , Mds-treatment , Myelodysplastic-syndromes-treatment , Lower-risk-mds , Ker-050 , Variant-allele-frequency , Luspatercept

Retrospective Claims Data and Patient Reported-Outcomes from COMMANDS Trial in Lower-Risk MDS

Amy DeZern, MD, MHS, discusses a retrospective study on healthcare claims for patients with MDS treated with luspatercept and reviews patient-reported outcomes from the COMMANDS trial.

Amy-dezern , Evolving-treatment-landscape , Myelodysplastic-syndromes , Claims-data , Patient-reported-outcomes , Mds , Mds-treatment , Myelodysplastic-syndromes-treatment , Ash-2023 , Real-world-outcomes , Luspatercept

Unmet Needs and Adverse Event Management for Patients With Lower-Risk MDS and Symptomatic Anemia

Hematologist-oncologists address adverse event management and discuss the unmet needs of patients with lower-risk MDS and symptomatic anemia.

Evolving-treatment-landscape , Myelodysplastic-syndromes , Adverse-event-management , Patients-with-lower-risk , Mds , Patient-case , Patient-profile , Symptomatic-anemia , Unmet-needs , Ring-sideroblasts , Esa

Updates to MDS Classification Complicate Yet Better Inform Treatment Navigation in MDS

Mikkael A. Sekeres, MD, MS, discusses the influence of therapeutic developments and conflicting classification systems on the management of MDS.

Florida , United-states , University-of-miami , Namrata-chandhok , Mikkaela-sekeres , World-health-organization , Division-of-hematology , International-prognostic-scoring-system , Sylvester-comprehensive-cancer-center , University-of-miami-health-system , International-consensus-classification , Onclive-state

Second-Line Treatment of Lower-Risk MDS With Symptomatic Anemia

Continuing their discussion on the first patient profile, the expert panel focuses on the second-line treatment of patients with lower-risk MDS and symptomatic anemia.

Evolving-treatment-landscape , Myelodysplastic-syndromes , Line-treatment , Mds , Patient-case , Patient-profile , Anemia , Sf3b1 , Luspatercept , Mds-treatment , Myelodysplastic-syndromes-treatment

Patient Profile 1: A 72-Year-Old Man With MDS

Andrew Brunner, MD, presents the profile of a 72-year-old man with MDS and the panel offers their initial impressions on the case, focusing on the treatment decisions.

Andrew-brunner , Evolving-treatment-landscape , Myelodysplastic-syndromes , Year-old-man-with , Mds , Patient-case , Patient-profile , Anemia , Sf3b1 , Luspatercept , Mds-treatment

First-Line Treatment of Lower-Risk MDS with Symptomatic Anemia

Amy DeZern, MD, MHS, provides clinical insights on the first-line treatment of patients with lower-risk MDS and symptomatic anemia.

Amy-dezern , Evolving-treatment-landscape , Myelodysplastic-syndromes , Line-treatment , Mds , First-line-treatment , First-line-therapies , Anemia , Symptomatic-anemia , Mds-treatment , Myelodysplastic-syndromes-treatment

Efficacy and Safety of Luspatercept versus Epoetin Alfa in Erythropoiesis-Stimulating Agent-Naïve Patients with Transfusion-Dependent Lower-Risk Myelodysplastic Syndromes: Full Analysis of the COMMANDS Trial

Guillermo Garcia-Manero, MD, presents data from the COMMANDS trial investigating luspatercept in erythropoiesis-stimulating agent-naive patients with transfusion-dependent lower-risk myelodysplastic syndromes.

San-diego , California , United-states , Guillermo-garcia-manero , International-prognostic-scoring-system , Epoetin-alfa , Erythropoiesis-stimulating-agent-na , Full-analysis , Partnership-with , Revised-international-prognostic-scoring-system , Commands-trial , Luspatercept