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Researchers provide ultrastructural details of SARS-CoV-2-infected respiratory epithelial cells


Researchers provide ultrastructural details of SARS-CoV-2-infected respiratory epithelial cells
A team of scientists from the United Kingdom recently investigated the ultrastructural details of the attachment, entry, and budding processes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the human airway epithelium. They have used a highly differentiated air-liquid interface cultures of airway epithelium to thoroughly investigate the viral infection cycle. The study is currently available on the
Background
SARS-CoV-2, the causative pathogen of coronavirus disease 2019 (COVID-19), is an enveloped RNA virus belonging to the Coronaviridae family. The virus primarily attacks human airway epithelial cells to initiate infection. Mechanistically, the receptor-binding domain (RBD) of the S1 subunit of the viral spike glycoprotein binds to angiotensin-converting enzyme 2 (ACE2), which is ubiquitously expressed at the apical surface of host airway epithelial ce ....

United Kingdom , Juan Gaertner Shutterstock , Sanchari Sinha Dutta , Juan Gaertner , Coronavirus Disease Covid 19 , Sars Cov 2 , Angiotensin Converting Enzyme 2 , Cell Membrane , Corona Virus , Electron Microscopy , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , Spike Protein , ஒன்றுபட்டது கிஂக்டம் , சஞ்சரி சீன்ஹா தத்தா , ஜுவான் கேர்ட்னெற் , செல் சவ்வு , கொரோனா வைரஸ் , எதிர் மின்னணு , எதிர் மின்னணு நுண்ணோக்கி , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி , ஸ்பைக் ப்ரோடீந் ,

Unusual fossil reveals last meal of prehistoric pollinator


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Unusual fossil reveals last meal of prehistoric pollinator
Aggregations of eudicot pollen and pollen-containing coprolites associated with Pelretes vivificus. a, Amber piece with P. vivificus, showing coprolites and one pollen aggregation. b-e, details of pollen under visible light (d) and confocal laser scanning microscopy (b, c, e). Scale bars: 1 mm (a), 50 μm in (b, e), 100 μm (c, d).
Chenyang Cai, Yanzhe Fu and Yitong Su
Ecological reconstruction of Pelretes vivificus vesting angiosperm flowers in the Burmese amber forest (~99 Ma).
Artwork by Mr. Jie Sun
Dorsal view of Pelretes vivificus, a Cretaceous short-winged flower beetle (Kateretidae) from Burmese amber (~99 Ma). Scale bar: 200 μm. ....

Erik Tihelka , Yanzhe Fu , Yitong Su , Jie Sun , Chenyang Cai , Liqin Li , Institute Of Geology , School Of Earth Sciences , Palaeontology Of The Chinese Academy Sciences , University Of Bristol , Nanjing Institute , Chinese Academy , Professor Chenyang Cai , Earth Sciences , Chinese Academy Of Sciences , ஜிே சூரியன் , நிறுவனம் ஆஃப் புவியியல் , பள்ளி ஆஃப் பூமி அறிவியல் , பல்கலைக்கழகம் ஆஃப் பிரிஸ்டல் , நான்ஜிங் நிறுவனம் , சீன கலைக்கழகம் , பூமி அறிவியல் , சீன கலைக்கழகம் ஆஃப் அறிவியல் , சுற்றுச்சூழல் அமைப்பு ,

Head-Mounted Microscope Captures Brain Activity in Freely Behaving Mice


Tracking activity at near cellular resolution could reveal how different regions of the brain interact
WASHINGTON – Researchers have developed a head-mounted miniature microscope that can be used to image activity from the entire outer part of the brain, or cortex, in freely behaving mice. When combined with implantable see-through skulls, the new microscope can capture the brain activity of mice for more than 300 days.
Mice are often used to study the brain because they have many of the same brain structures and connectivity as humans. The new microscope, known as the mini-mScope, offers an important new tool for studying how neural activity from multiple regions of the cortex contribute to behavior, cognition and perception. ....

United States , Mathewl Rynes , Daniel Surinach , Biophotonics Congress , Life Sciences , University Of Minnesota , Twin Cities , Optical Society , Brain Activity , ஒன்றுபட்டது மாநிலங்களில் , வாழ்க்கை அறிவியல் , பல்கலைக்கழகம் ஆஃப் மினசோட்டா , இரட்டை நகரங்கள் , ஒளியியல் சமூகம் , மூளை நடவடிக்கை , புகைப்பட கருவி ,

WA scientists shed light on continent formation


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WA scientists shed light on continent formation
Research from Western Australian scientists has shed new light on how the Earth’s first continental crust was formed.
The team of scientists, which included Dr Laure Martin and Mr Matvei Aleshin from The University of Western Australia and was led by the Geological Survey of Western Australia and Curtin University, measured compositions of oxygen in ancient granites in the Pilbara using the ion microprobe Cameca IMS1280 at UWA.
The scientists found that the water required to produce the granites did not come from above but was supplied from the mantle, which is the thick layer below the Earth’s crust. ....

Western Australia , Matvei Aleshin , Laure Martin , Curtin University , Centre For Microscopy , National Collaborative Research Infrastructure Strategy , Geological Survey Of Western Australia , University Of Western Australia , Western Australian , Geological Survey , Hugh Smithies , State Government , Exploration Incentive Scheme , Microscopy Australia , Federal Government , மேற்கு ஆஸ்திரேலியா , கவரும் மார்டின் , கர்டின் பல்கலைக்கழகம் , மையம் க்கு நுண்ணோக்கி , தேசிய கூட்டு ஆராய்ச்சி உள்கட்டமைப்பு மூலோபாயம் , புவியியல் கணக்கெடுப்பு ஆஃப் மேற்கு ஆஸ்திரேலியா , பல்கலைக்கழகம் ஆஃப் மேற்கு ஆஸ்திரேலியா , மேற்கு ஆஸ்திரேலிய , புவியியல் கணக்கெடுப்பு , நிலை அரசு , ஆய்வு ஊக்கத்தொகை திட்டம் ,

Search for strange Skyrmion phenomenon fails but finds even stranger magnetic beaded necklace with computer memory storage


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Search for strange Skyrmion phenomenon fails but finds even stranger magnetic beaded necklace with computer memory storage
University of Warwick physicists set out to find Skyrmions, only to find near-identical object with distinctive qualities that they have named an incommensurate spin crystal
Scientists looked for the signs of the magnetic spin texture in ultra-thin materials only a few atoms thick
Physicists have great interest in the potential of Skyrmions frequently detected by their ambiguous, bulk electrical measurements.
This new discovery could point the way for a new basis for technologies in computer memory and storage
Physicists on the hunt for a rarely seen magnetic spin texture have discovered another object that bears its hallmarks, hidden in the structure of ultra-thin magnetic films, that they have called an incommensurate spin crystal. ....

United Kingdom , Sam Seddon , Marin Alexe , Royal Society , Nature Communications , University Of Warwick , United Kingdom Research , Magnetic Force Microscopy , University Of Warwick Department Physics , Sciences Research Council , Topological Hall , Warwick Department , Professor Marin Alexe , Physical Sciences Research Council , Quantum Computer , Research Council , ஒன்றுபட்டது கிஂக்டம் , சாம் ஸெடந் , மரின் அலெக்ஸ் , அரச சமூகம் , இயற்கை தகவல்தொடர்புகள் , பல்கலைக்கழகம் ஆஃப் வார்விக் , ஒன்றுபட்டது கிஂக்டம் ஆராய்ச்சி , காந்த படை நுண்ணோக்கி , பல்கலைக்கழகம் ஆஃப் வார்விக் துறை இயற்பியல் , அறிவியல் ஆராய்ச்சி சபை ,