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Lemon Peel Extract on Oxidative Stress in Rat Heart Cells


Statistical Analysis
Three parallel experiments were performed to obtain the average value, which was determined using SPSS 23 statistical software and compared between groups using independent-sample t tests and a one-way analysis of variance method. Significant differences between groups were observed at the
P 0.05 level.
DPPH and ABTS Radical Scavenging Abilities of LPE
Figure 1 shows the dose-response relationship of DPPH and the ABTS radical scavenging ability of LPE. The ability of LPE to scavenge DPPH and ABTS radicals increased with increasing concentrations of LPE from 0 to 120 μg/mL. Moreover, the Vc positive control group had lower DPPH and ABTS radical scavenging abilities than LPE. ....

United States , Santa Clara , Shanghai Yiji Biology Co Ltd , Jiancheng Bioengineering Institute , Procell Life Science Technology Co Ltd , Sichuan Province , Performance Liquid Chromatographic Detection , Radical Scavenging Ability , Procell Life Science , Cell Viability Using , Thermo Fisher Scientific , Nanjing Jiancheng Bioengineering Institute , Stepone Plus , Oxidative Damage Induced , Lemon Peel Extract , ஒன்றுபட்டது மாநிலங்களில் , சாந்தா கிளாரா , ஸிச்வாந் மாகாணம் , ப்ரோசேல்ல் வாழ்க்கை அறிவியல் , தெர்மோ மீனவர் அறிவியல் , எலுமிச்சை தலாம் பிரித்தெடுத்தல் ,

Punicalagin may be a potent drug for rheumatoid arthritis


1
1Department of Nephrology, Kidney and Urology Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, ShenZhen, Guandong, People’s Republic of China;
2Department of Rheumatology, The First Affiliated Hospital of Jinan University, Guangzhou, Guandong, People’s Republic of China;
3Department of Rheumatology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guandong, People’s Republic of China
These authors contributed equally to this work
Background: The aggressive phenotype of fibroblast-like synoviocytes (FLSs) is essential in the synovitis and bone destruction in rheumatoid arthritis (RA). Punicalagin is a natural polyphenol extracted in pomegranate juice, which possesses antioxidant, anti-inflammatory and anti-tumor properties suggesting it may be a potent drug for RA therapy. However, there is paucity of information on its effect in RA. ....

United States , San Leandro , Eteläuomen Läi , San Diego , Thiazol Tetrazolium Cytotoxicity , Alpha Innotech , National Institutes Of Health , Jiancheng Bioengineering Institute , American College Of Rheumatology , Laboratory Animal , Cell Signaling Technology , Laboratory Animal Company , Ethics Committee , Technology Co , Us National Institutes Of Health , Nuclear Factor Kappa , American College , Clinical Research Ethics Committee , First Affiliated Hospital , Sun Yat Sen University , Animal Care , Imaging Kit , Pro Inflammation Cytokines , Assay Diluent , Wash Buffer , Healing Assay ,

Carbon Monoxide Releasing Molecule-3 Enhances Osteogenic Differentiati


7,8 and organ protection from ischemia/reperfusion injury.
9,10 Newly synthesized transition metal carbonyl-compounds, CO release molecules (CORMs), are effective in regulating CO release in vivo and in vitro in appropriate circumstances.
11 These CO releasing molecules can therefore be used as the new carrier to provide exogenous CO. CORM-3 [tricarbonylchloro (glycinato) ruthenium (II)] is completely soluble in water with fast release of CO when dissolved in a physiological solution.
By releasing CO, CORMs also induce an anti-inflammatory effect. Our previous study showed that CORM-2 reduced periodontal inflammation and alveolar bone resorption in rats with experimental periodontitis.
13 We also reported CORM-3 suppressed the expression of adhesion molecules in human gingival fibroblasts co-stimulated by tumor necrosis factor-α and interleukin-1 β, ....

United States , Eteläuomen Läi , Zheng Hai , Franklin Lakes , L Trizol Takara , Green Takara Biotechnology Co Ltd , Cyagen Biosciences Inc , Ge Healthcare Life Sciences , Proteintech Group Inc , Jiancheng Bioengineering Institute , Shandong University , Merck Kga , Kit Jiancheng Biological Inc , Solarbio Science Technology Co Ltd , Ethics Committee Of The School , Olympus Corp , Vital River Laboratory Animal Technology Co Ltd , Ethical Committee Of School , Beyotime Institute Of Biotechnology , Dojindo Molecular Technologies Inc , Roche Ltd , Co Ltd , Shandong University Jinan , Laboratory Animals , Oil Redo Cyagen Biosciences , Sigma Aldrich ,