SSc Autoantibody Identified with Link to GI Dysfunction
If validated as a biomarker, anti-gephyrin autoantibodies could help identify patients at higher risk for GI symptoms like constipation.
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If validated as a biomarker, anti-gephyrin autoantibodies could help identify patients at higher risk for GI symptoms like constipation.
A daily prednisolone dose of less than 5 mg was not associated with increased cardiovascular risk, whereas a dose of 5 mg or more doubled the risk for major adverse cardiovascular events.
The biotech company, which slightly raised its outlook for full-year revenue and profit, said it currently expects a deal to acquire Horizon Therapeutics to close by mid-December.
The autoantibodies anti-POLR3 and monospecific anti-Ro52 were associated with increased cancer risk, while anti-centromere and anti-U1RNP were tied to reduced risk.
The two tool scores could help determine who can be managed in primary care and who may qualify for intervention studies.