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Ultra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses

Objective To evaluate the existing meta-analytic evidence of associations between exposure to ultra-processed foods, as defined by the Nova food classification system, and adverse health outcomes.

Design Systematic umbrella review of existing meta-analyses.

Data sources MEDLINE, PsycINFO, Embase, and the Cochrane Database of Systematic Reviews, as well as manual searches of reference lists from 2009 to June 2023.

Eligibility criteria for selecting studies Systematic reviews and meta-analyses of cohort, case-control, and/or cross sectional study designs. To evaluate the credibility of evidence, pre-specified evidence classification criteria were applied, graded as convincing (“class I”), highly suggestive (“class II”), suggestive (“class III”), weak (“class IV”), or no evidence (“class V”). The quality of evidence was assessed using the GRADE (Grading of Recommendations, Assessment, Development, and Evaluations) framework, categorised as “high, ....

United States , Western Australia , United Kingdom , South Korea , New Zealand , South Australia , American Nutrition Association , Nutrition Research Australia , International Agency For Research On Cancer , Institute For Physical Activity , Monash University , Australian Research Council Future Fellowship , Australian Research Council , Gut Brain Congress , Mood Centre , Incorporated Psychiatric Annals , Translation Research Accelerator Program , International Society For Nutritional Psychiatry Research , Research Council Synergy Grant , Waterloo Foundation , Francis Group Healthy , Journal Of The American Society Nephrology , Cardiometabolic Health , Sclerosis Research Australia , Food Mood Centre , Research Council ,

Effect of exercise for depression: systematic review and network meta-analysis of randomised controlled trials

Objective To identify the optimal dose and modality of exercise for treating major depressive disorder, compared with psychotherapy, antidepressants, and control conditions.

Design Systematic review and network meta-analysis.

Methods Screening, data extraction, coding, and risk of bias assessment were performed independently and in duplicate. Bayesian arm based, multilevel network meta-analyses were performed for the primary analyses. Quality of the evidence for each arm was graded using the confidence in network meta-analysis (CINeMA) online tool.

Data sources Cochrane Library, Medline, Embase, SPORTDiscus, and PsycINFO databases.

Eligibility criteria for selecting studies Any randomised trial with exercise arms for participants meeting clinical cut-offs for major depression.

Results 218 unique studies with a total of 495 arms and 14 170 participants were included. Compared with active controls (eg, usual care, placebo tablet), moderate reductions ....

New Zealand , United Kingdom , United States , Paul Taylor , Michael Noetel , Philip Parker , Daniel Gallardo , Jemima Spathis , Lachlan Mckee , Mark Moresi , Juliette Grosvenor , Pozo Cruz , Rebecca Pagano , Stuart Biddle , John Mahoney , Roberta Vasconcellos , Hugh Arnott , Taren Sanders , Chris Lonsdale , Benjamin Varley , Lisa Pagano , Cochrane Comparing Multiple Interventions Methods Group , American Psychiatric Association , National Institute For Health , Statistical Manual Of Mental Health Disorders , Cochrane Library ,

Brian Nosek: A Crisis of Research Reproducibility – Yale Scientific Magazine

Brian Nosek: A Crisis of Research Reproducibility – Yale Scientific Magazine
yalescientific.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from yalescientific.org Daily Mail and Mail on Sunday newspapers.

Brian Nosek , Image Courtesy Of Center , Arnold Foundation , University Of Virginia , Image Courtesy , Open Science , Project Implicit , Open Science Framework ,