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6 Similarly, intrastromal Amphotericin-B (ISAMB) has also been employed successfully for targeted drug delivery. 7 In an experimental study in rabbit eyes by Mimouni et al, intrastromal natamycin (ISNTM) was employed successfully for treatment of Fusarium keratitis. 8 While many studies have individually described the utility of these drugs for intrastromal injections in recalcitrant fungal keratitis, there is a relative paucity of peer-reviewed literature prospectively comparing the safety and efficacy of these drugs. We conducted a randomized clinical trial to determine and compare the saf...

Study suggests that excessive daytime sleepiness is chronotype-dependent. School start times could be shifted to a later hour to prolong sleep and reduce EDS.

Wednesday, May 26, 2021 The COVID-19 pandemic underscored the need for government transparency, accountability and citizen engagement. In response, Argentina, Colombia and Ecuador have adopted open parliament plans and regulations that focus on increasing transparency and access to information; accountability; citizen participation; and ethics and probity.   Argentina In Argentina, NDI partner Legislative Directory (Directorio Legislativo, DL) was among roughly 30 civil society organizations who actively collaborated with the Chamber of Deputies to co-create the first open parliament action ...

Patients and Methods Study Design This retrospective observational study was conducted on COVID-19 patients (positive polymerase chain reaction [PCR] results via nasopharyngeal swab) between June 1 and mid July 2020. Patients were recruited from Kasr Al-Aini School of Medicine, Cairo University Hospitals. We included all adult patients (18 −75 years) suffering from mild or moderate COVID-19 infection according to World Health Organization (WHO) criteria for the clinical management of COVID-19. 11 Patients were excluded if they had severe COVID-19 disease, were hospitalized, or had unavailab...

2 1Wits Donald Gordon Medical Centre, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa; 2Steve Biko Centre for Bioethics, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa Correspondence: Harriet Rosanne Etheredge Wits Donald Gordon Medical Centre, 1st Floor, Max Price Building, 27 Eton Road, Parktown, Johannesburg, 2193, South Africa Tel +27 113566395 Abstract: This paper argues that there is little difference between opt-in and opt-out organ donation systems for increasing donor numbers when used in isolation. I...