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The Google subsidiary solved a fundamental problem in biology but didn’t promptly share its solution. So a University of Washington team tried to re-create it.

Determining Protein Structure with Electron Microscopy Image Credit: Sergei Drozd/Shutterstock.com Gaining a deeper level of understanding of a protein’s structure opens the door to fine-grain detail on how the protein functions and what its purpose may be. It also gives scientists the opportunity to develop hypotheses on how they affect the protein, as well as how to control and modify it. This means that in knowing a protein’s structure, scientists can work on creating site-directed mutations with the purpose of changing the protein’s function. This capability is vita...

Experiment with 2533 fragments compounds generates chemical map to future antiviral agents  Principal Beamline Scientist on I04, Frank von Delft.  New research published in Science Advances provides a template for how to develop directly-acting antivirals with novel modes of action, that would combat COVID-19 by suppressing the SARS-CoV-2 viral infection. The study focused on the macrodomain part of the Nsp3 gene product that SARS-CoV-2 uses to suppress the host cell’s natural antiviral response. This part of the virus’s machinery, also known as Mac1, ...

Mar 11 2021 Read 205 Times Author: Robert P. Rambo on behalf of Diamond Light Source Ltd Free to read Unlock In 2020, the most significant application of Soft-condensed matter (SCM) science was, undoubtedly, the development of the COVID vaccines by Pfizer-BioNTech and Moderna which are composed of a synthetic messenger RNA encapsulated within a lipid nanoparticle [1].  SCM science drives continued improvements to quality of life as SCM science is integral to a broad range of industrial sectors.  These sectors include food safety and waste, agriculture, polymers, coatings...

He measures to tackle debt his main rival Alberto Fernandez says he'll spend more on social welfare Katie Watson reports President Mauricio Macri ran on a campaign of 0 poverty in 2015 but 4 years later the country is in crisis inflation is at 50 percent and one in 3 people here now live in poverty so Argentinians will be deciding which of the 2 top candidates they think can change the direction of is ailing economy they stick with reform minded Mr machree and hope he can do a better job in his 2nd term or opt for a relatively unknown Albert of a none this who with former President Cristina F...