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This multicenter randomized clinical trial compares the effects of 12 mg/d vs 6 mg/d of dexamethasone in patients with COVID-19 and severe hypoxemia.
This study compares the effect of convalescent plasma vs no convalescent plasma on the outcome of organ support–free days in the hospital among critically ill a
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Regeneron mAb cocktail benefits hospitalized patients with no natural SARS-CoV-2 antibody response Researchers reporting on findings from the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial in the UK are recommending that any therapeutic use of REGEN-COV may be best restricted to individuals without detectable antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The RECVORY Collaborative Group says that among patients hospitalized with coronavirus disease 2019 (COVID-19), REGEN-COV reduced 28-day mortality by about one-fifth in those who were seronegativ...
COVID-19: why critically ill patients in Africa are taking a bigger hit The Conversation 22 May 2021, 20:43 GMT+10 In March 2020, those of us living on the African continent were terrified about what would happen. We had watched Wuhan and then Italy get overrun by Covid-19. These were environments far more resourced than Africa . We knew that we had a limited healthcare workforce. And we have estimated that there was about one critical care bed per 100 000 population on the continent. The average across Europe was over 11 per 100 000 population. What scared us even more was a lack of informat...
Columbia University's Mailman School of Public Health A randomized double-blind controlled trial of convalescent plasma for adults hospitalized with severe COVID-19 found that mortality at 28 days in the treatment arm was half the rate seen in the control arm (12.6% vs. 24.6%), although treatment was not associated with other improvements in clinical status. The study was led by investigators from the Center for Infection and Immunity at Columbia University Mailman School of Public Health; Columbia University Irving Medical Center; ICAP at Columbia University; Instituto Nacional de Infectolog...