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Researchers find CXCR6 gene plays a role in COVID-19 severity

Researchers in the United States have conducted a study demonstrating that a gene called CXCR6 (C-X-C Motif Chemokine Receptor 6) may play an important role in determining the severity of COVID-19. ....

United States , New York , Cornell University , Sally Robertson , C Xc Motif Chemokine Receptor , Texas Health Science Center , Coronavirus Disease Covid 19 , Sars Cov 2 , Corona Virus , Gene Expression , Intensive Care , ஒன்றுபட்டது மாநிலங்களில் , புதியது யார்க் , கார்னெல் பல்கலைக்கழகம் , சாலி ராபர்ட்சன் , டெக்சாஸ் ஆரோக்கியம் அறிவியல் மையம் , கொரோனா வைரஸ் , கீந் வெளிப்பாடு , தீவிர பராமரிப்பு ,

How does the SARS-CoV-2 E484K mutation increase viral fitness?

How do mutations benefit SARS-CoV-2? To explore this, a team of researchers from China took a closer look at the physical interactions that occur between the proteins after viral mutation. ....

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Live attenuated SARS-CoV-2 vaccine candidate shows protective efficacy in vivo

A new preprint on the bioRxiv server describes the development of a live attenuated vaccine candidate to counter the growing threat of the COVID-19 pandemic. ....

Liji Thomas , Coronavirus Disease Covid 19 , In Vivo , Sars Cov 2 , Angiotensin Converting Enzyme 2 , Corona Virus , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , Weight Loss , இல் விவோ , கொரோனா வைரஸ் , சர்வதேச பரவல் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி , எடை இழப்பு ,

Llama-derived nanobodies show neutralizing activity against SARS-CoV-2 variants of concern in vitro

Llama-derived nanobodies show neutralizing activity against SARS-CoV-2 variants of concern in vitro
With the emergence of new variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic, the prospect of effective containment of viral transmission has receded. Not only are they more transmissible than the earlier strains, but they also offer partial resistance to neutralization by existing antibodies in some cases. Moreover, they can evade detection by current antigen detection kits because of mutations in the spike protein with each of the new variants.
Better tests needed
This development could cause many more false-negative diagnoses to arise, giving rise to a more devastating wave of community spread. The need for more up-to-date antibody arrays is obvious. A new preprint on the ....

South Africa , United Kingdom , South African , Liji Thomas , Immunized Llama Effectively Bind Targets , South African Strains , Coronavirus Disease Covid 19 , Sars Cov 2 , Binding Affinity , Corona Virus , In Vitro , Monoclonal Antibody , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , Spike Protein , ஒன்றுபட்டது கிஂக்டம் , சர்வதேச பரவல் , பிணைப்பு இன உறவு , கொரோனா வைரஸ் , இல் விட்ரோ , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி , ஸ்பைக் ப்ரோடீந் ,

Advancements in DNA vaccines against COVID-19

Advancements in DNA vaccines against COVID-19
The coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to spread globally. The total number of infections has reached 109.88 million globally with 61.88 million reported as recovered.
The rapid spread of the pathogen and the increasing number of cases highlight the need for an effective and safe vaccine. As vaccination efforts roll out in many countries, new types of vaccines, like deoxyribonucleic acid (DNA) vaccines, are under research..
Researchers at the Department of Pharmacy, Pelotas, Rio Grande do Sul, in Brazil, explained the functionality and efficacy of DNA vaccines in pandemic scenarios. They also provided a summary of the DNA vaccines being tested in clinical trials. ....

Rio Grande Do Sul , New South Wales , Zydus Cadila , Angela Betsaidab Laguipo , Entos Pharmaceuticals Inc , Geneone Life Science Inc , Providence Health Services , University Of Sydney , Anges Takara Bio Osaka University , Genexine Consortium , Bionet Co , Life Sciences , Department Of Pharmacy , Inovio Pharmaceuticals , Symvivo Corporation , Angela Betsaida , Rio Grande , Protein Plasmid , Providence Health , Geneone Life Science , Rottapharm Biotech , Middle East , Corona Virus , Coronavirus Disease Covid 19 , Immune System , Sars Cov 2 ,