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Interstitial macrophages trigger severe COVID in the lung

SARS-CoV-2 could proliferate in the lungs causing severe COVID-19 through a special type of immune cell. A group of scientists from Stanford University observed how this coronavirus infected interstitial macrophages through a CD209 receptor, triggering the inflammatory response observed in hospitalized patients.

Stanford-university , Bioworld-science , Patents , Coronavirus , Covid-19 , Sars-cov-2 , University-of-california , An-francisco , Severe-covid , Stanford-university-school-of-medicine , Immune

Opinion: Pharmac's funding gap leaves New Zealand babies vulnerable to RSV

Winter is coming, and with it the spectre of respiratory syncytial virus (RSV) looms large for our youngest and most vulnerable children. Yet despite the...

New-zealand , Australia , Western-australia , Opinion , Pharmacs , Funding , Gap , Leaves , New , Zealand , Babies

Pulmonology Month in Review: March 2024

In this Month in Review article for March, news on topics such as asthma and the impacts of pollution in the pulmonology field were highlighted.

Texas , United-states , Quebec , Canada , Montreal , Natachad-emerson , Tilmann-schober , Jamie-ostroff , University-of-texas-at-austin , American-college-of-surgeons , College-of-natural-sciences , Dell-medical-school

SPMC sees hike in respiratory-related diseases due to temperature surge

AN OFFICIAL from the Southern Philippines Medical Center (SPMC) said they expect an increase in respiratory-related diseases caused by the increasing temperatures.

Philippines , Niel-ayala-otacan , Deltas-aguilar , Department-of-pediatrics , Southern-philippines-medical-center , Infectious-disease-cluster , Reemerging-disease , Ayala-malls-abreeza , Ayala-otacan , Spmc , Respiratory-related-diseases , Health

AI-driven research identifies pulmonary fibrosis target and inhibitor

Deep learning algorithms have enabled the discovery of molecular structures of interest in biomedicine to design treatments against aggressive diseases such as idiopathic pulmonary fibrosis (IPF). Scientists at Insilico Medicine Inc. selected a target for IPF using artificial intelligence (AI), then designed an inhibitor to block it, and tested it in vitro, in vivo, and in clinical trials.

Scientists-at-insilico-medicine-inc , Insilico-medicine , Bioworld-science , Respiratory , Insilico-medicine-inc- , Idiopathic-pulmonary-fibrosis , Tnik , Tnik-inhibitors , Artificial-intelligence , Drug-design , Rug-delivery-and-technologies

Rapt slapped with phase II hold on CCR4 prospect

On the verge of top-line data from its phase IIb trial with oral small-molecule CC chemokine receptor 4 (CCR4) antagonist zelnecirnon in atopic dermatitis (AD), due around the middle of this year, Rapt Therapeutics Inc. said the U.S. FDA has imposed a clinical hold on that study with the otherwise promising drug, also known as RPT-193, in AD as well as the phase IIa trial with the same compound in asthma.

Rapt-therapeutics-inc , Rapt-therapeutics , Rapt-therapeutics-inc- , Zelnecirnon , Rpt-193 , Atopic-dermatitis , Asthma , Clinical-hold , Bioworld , Clinical , Respiratory

Delhi Air Pollution: National CapitalтАЩs Poor Air Quality Spikes Respiratory, Cardiac Problems, Say Doctors

“The primary contributing factor to these health issues is the presence of smog, which directly irritates the lungs and throat, particularly affecting those with pre-existing respiratory conditions,” she explained.

📰 Delhi Air Pollution: National Capital’s Poor Air Quality Spikes Respiratory, Cardiac Problems, Say Doctors.

Manipal , Karnataka , India , Delhi , New-delhi , Dwarka , Gujarat , Puneet-khanna , Anshum-aneja-arora , Sushila-kataria , Gas-chamber , National-capital-turns