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Newly developed organoid model can be used to study thymus function

Researchers from the Organoid group have developed a new organoid model that can be used to study the thymus.

Hubrecht-institute , Cell-reports , Sangho-lim , Thymus , Acteria , Lood , Ell , Mmune-system , Aboratory , Icroscopy , Ncology

Human mini-lungs mimic animal response to nanomaterials

Human mini-lungs grown by University of Manchester scientists can mimic the response of animals when exposed to certain nanomaterials.

United-kingdom , Manchester , Kostas-kostarelos , Rahaf-issa , Sandra-vranic , University-nanocell-biology-lab , Centre-for-nanotechnology , University-of-manchester , Nanocell-biology-lab , Lungs , Ell , Ibrosis

Scientists identify signaling pathway in liver cells linked to fibrosis

A healthy liver filters all the blood in your body, breaks down toxins and digests fats. It produces collagen to repair damaged cells when the liver is injured.

Switzerland , Israel , San-diego , California , United-states , University-of-california-san-diego , Swiss , Jerrold-olefsky , Tatiana-kisseleva , Avrahamm-libster , Theresav-rohm , Zea-borok

Novel lab-grown mini-colons can accurately mimic the development of colorectal tumors

In a breakthrough for cancer research, scientists at EPFL have created lab-grown mini-colons that can accurately mimic the development of colorectal tumors, offering a powerful new tool for studying and testing treatments for the disease.

Luis-francisco-lorenzo-mart , Freddy-radtke , Ecole-polytechnique-federale , Institute-of-human-biology , Roche-institute-of-human-biology , Polytechnique-federale-de-lausanne , Cancer , Olorectal , Olorectal-cancer , Esearch , Ell , Ell-culture

Household chemicals endanger brain's myelin-forming cells

Study uncovers how environmental chemicals, specifically organophosphate flame retardants and quaternary compounds, negatively affect oligodendrocyte development, implicating them in potential neurodevelopmental risks such as ADHD and autism, by employing an innovative high-throughput screening approach on mouse and human stem cell-derived models.

United-states , International-society-for-stem-cell-research , National-health , National-institutes-of-health , Nutrition-examination-survey , Case-western-reserve-university-institutional-animal-care , United-states-environmental-protection-agency , Nature-neuroscience , Hyperactivity-disorder , International-society , Stem-cell-research

Study reveals distinct molecular features of proximal and distal colon cancers

The colon is often thought of as one organ, but the right and left parts of the colon have different molecular features in cancers.

Wuhan , Hubei , China , Huazhong , Hariharan-easwaran , Malcolm-brock , Sara-jayne-thursby , Lijing-yang , Stephenb-baylin , Cynthia-zahnow , Tina-largent , Johns-hopkins

Revolutionary stem cell culture method produces full model of human central nervous system

The first stem cell culture method that produces a full model of the early stages of the human central nervous system has been developed by a team of engineers and biologists at the University of Michigan, the Weizmann Institute of Science, and the University of Pennsylvania.

Museum-of-science , Massachusetts , United-states , Cambridge , Cambridgeshire , United-kingdom , Boston , State-of-michigan , Michigan , Ann-arbor , Guo-li-ming , Insoo-hyun

"Laboratory testicles" could solve male infertility mysteries

The testis is responsible for sperm production and testosterone synthesis. Abnormalities in testis development and function lead to disorders of sex development (DSD) and male infertility. Currently, no in vitro system exists for modeling the testis.

Cheli-lev , Aviya-stopel , Nitzan-gonen , International-journal-of-biological-sciences , Goodman-faculty-of-life-sciences , Institute-of-nanotechnology , Ilan-university , Stav-dahari , Goodman-faculty , Life-sciences , Advanced-materials , Bar-ilan-university