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Clinical Data With Pacritinib in Patients With Myelofibrosis

Centering discussion on the JAK inhibitor pacritinib, expert panelists review data from recent clinical trials and consider how they inform real-world use of this agent. ....

Data With Pacritinib , Patients With Myelofibrosis , Mf Cancer , Primary Myelofibrosis , Jak Inhibitors , Jak Inhibition , Novel Therapy , Persist 2 Trial , Persist 2 Study , Irak Signaling , Clinical Trials , Patient Selection , Patient Eligibility , Pacifica Trial , Pacifica Study ,

Dr Franco Locatelli: Assessing Ruxolitinib Treatment in Pediatric Patients With cGvHD

Franco Locatelli, MD, PhD, a professor and hematologist from Italy, discusses results from the the phase 2 REACH 5 studies assessing the use of ruxolitinib in pediatric patients with chronic graft versus host disease (cGvHD). ....

Franco Locatelli , University Of Rome , Department Of Pediatric Hematology , Pediatric Hematology , Gesu Children , Rare Disease , Chronic Graft Versus Host Disease ,

Dr Martin Griesshammer: Treatment Options, Optimization for Patients with Polycythemia Vera

Martin Griesshammer, MD, PhD, Johannes Wesling University Clinic, discusses past and current efforts to improve treatment options for patients with polycythemia vera. ....

Francesca Palandri , Martin Griesshammer , Johannes Wesling University Clinic , Department Of Haematology , Palliative Care , Johannes Wesling University , Rare Disease , Polycythemia Vera ,

Ruxolitinib improves symptoms in patients with disabling pansclerotic morphea

1. In this case series, ruxolitinib was associated with improved inflammatory markers in patients with disabling pansclerotic morphea (DPM). 2. Ruxolitinib use was also associated with improved clinical symptoms in treated patients with DPM. Evidence Rating Level: 1 (Excellent) Study Rundown: DPM is a severe autoinflammatory disorder characterized by poor wound healing with rapidly progressive ....

Minute Medicine Inc , Rating Level , Signal Transducer , Janus Kinase , Chronic Disease , Disabling Pansclerotic Morphea , Pansclerotic Morphea ,

Amit Pandya, MD: Ruxolitinib Cream in Real-World Vitiligo Patients of Color

The trial investigator reviews disparities in patient needs and treatment outcomes based on their skin complexion, 1 year after ruxolitinib's FDA approval. ....

United States , Amit Pandya , University Of Texas Southwestern Medical Center , American Academy Of Dermatology , Drug Administration , American Academy , Maui Derm , Colorado Springs , Pigmentory Disorders , Palo Alto Medical Foundation , Texas Southwestern Medical Center , Skin Of Color ,