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Researchers discover immunity genetics leading to worse COVID outcomes for men

Researchers discover immunity genetics leading to worse COVID outcomes for men
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COVID-19 Collection

COVID-19 Collection
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United kingdomCoted ivoireIvory coastAnkit bharatPeter watkinsonSamuel kimSindhu vangetiReinhard busseAlexander supadyTom wingfieldPeter macphersonAnna schultzeBrianj lipworthCarlos guijarroJ randall curtisStuartb mazzone

COVID-19 Collection

Coted ivoireIvory coastAnkit bharatSrinivas murthyXavier lescurePeter watkinsonSamuel kimSindhu vangetiReinhard busseAlexander supadyTom wingfieldPeter macphersonAnna schultzeBrianj lipworthCarlos guijarroJ randall curtis

Two vaccine doses boost antibody levels in airways after Covid

Antibodies in the airways quickly wane after SARS-CoV-2 infection, but vaccination results in a strong increase in antibody levels, especially after

Piac gubischDeleah pettieJohan normarkFarangies ghafoorSindhu vangetiJulia svenssonLauren carterNeilp kingMichael murphyMeng yuJan albertMona eiseleMax bellKarolinska institutetAnna warnqvistLida azizmohammadi

Myeloid immune cells in blood tied to severe COVID-19

Date Time Myeloid immune cells in blood tied to severe COVID-19 Individual variations in how the immune system responds to SARS-CoV-2 appear to impact the severity of disease. Researchers at Karolinska Institutet have now been able to show that patients with severe COVID-19 have significantly elevated levels of a certain type of immune cells in their blood, called myeloid-derived suppressor cells. The study published in the Journal of Clinical Investigation may bring an increased understanding of how early immune responses impact disease severity. Anna Smed Sörensen. Photo: Ulf Sirborn. Most individuals with COVID-19 develop mild to moderate symptoms and recover without needing hospital treatment. In severe cases, however, COVID-19 can lead to respiratory failure or even death. It is not yet known why the severity of disease varies so much between patients.

United statesMeng yuHolden maeckerInga szurgotSindhu vangetiIsabella badolatiJan albertMax bellKarolinska institutetNiclas johanssonAlberto cagigiMaximilian julius lautenbachRyan falck jonesUlf sirbornKlara lenartFang lin