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NAN Open-Design Upright Microscope | Sutter Instrument Company | Aug 2022 - Vimarsana News

NAN Open-Design Upright Microscope | Sutter Instrument Company | Aug 2022

The Sutter Instrument NAN™ is a focusing nosepiece microscope designed for patch clamp electrophysiology or material science. Highly stable, adj

Frontiers | Stiffening of Circumferential F-Actin Bands Correlates With Regenerative Failure and May Act as a Biomechanical Brake in the Mammalian Inner Ear - Vimarsana News

Frontiers | Stiffening of Circumferential F-Actin Bands Correlates With Regenerative Failure and May Act as a Biomechanical Brake in the Mammalian Inner Ear

The loss of inner ear hair cells causes permanent hearing and balance deficits in humans and other mammals, but nonmammals recover after supporting cells (SCs) divide and replace hair cells. The proliferative capacity of mammalian SCs declines as exceptionally thick circumferential F-actin bands develop at their adherens junctions. We hypothesized that the reinforced junctions were limiting regenerative responses of mammalian SCs by impeding changes in cell shape and epithelial tension. Using micropipette aspiration and atomic force microscopy, we measured mechanical properties of utricles fro...

Multiphoton Microscopy: Imaging Brains of Mice on the Go - Vimarsana News

Multiphoton Microscopy: Imaging Brains of Mice on the Go

Scientists can now follow the activity of multiple neurons as a mouse sees, responds and behaves, thanks to advances in multiphoton microscopy.

Neuronal Imaging for Central Nervous Systems Drugs - Vimarsana News

Neuronal Imaging for Central Nervous Systems Drugs

Neuronal Imaging for Central Nervous Systems Drugs Sponsored by Photon etcJul 27 2018 The Biosimulation and Imaging platform for new Central Nervous System drugs (BICNSD) is a 3 year project for the validation and development of a unique service based on biosimulation and imaging using two synergistic platforms. This will boost drug development and discovery through tracking drug candidates’ actions at molecular and subcellular levels and having a greater understanding of Central Nervous System (CNS) diseases. Figure 1. Composition of a synapse The multiplex cellular fluores...