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Recently published studies of two different immunologic agents show beta-cell preservation in people with newly diagnosed disease, but no differences in glycemic control and ongoing insulin requirement. ....
1. Mean HbA1c reduction at 26 weeks was comparable in the weekly icodec and daily degludec groups. 2. The risk of hypoglycemia was significantly higher among patients taking weekly insulin icodec compared to those taking daily insulin degludec. Evidence Rating Level: 1 (Excellent) Study Rundown: First-line therapy for type 1 diabetes includes a combination of ....