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New technology Helps in Oral Delivery of Insulin by Angela Mohan on April 6, 2021 at 3:04 PM New insulin oral delivery system could replace traditional subcutaneous injections without the side effects caused by frequent injection. Using prepared layers of nanosheets with insulin loaded in between layers to protect it, researchers developed gastro-resistant imine-linked-covalent organic framework nanoparticles (nCOFs) that exhibited insulin protection in the stomach as well in diabetic test subjects whose sugar levels completely returned to normal within two hours after swallowing the nanoparticles. Led by NYUAD s Research Scientist Farah Benyettou and Program Head of Chemistry Ali Trabolsi, the findings were published in ....
HCAs are a promising risk indicator of type 2 diabetes A series of studies led by researchers from Hong Kong Baptist University (HKBU) have revealed that hyocholic acid and its derivatives (collectively known as HCAs), a component of bile acids that facilitate fat digestion, are a promising risk indicator of type 2 diabetes. The strong efficacy of HCAs in regulating blood glucose levels and protecting against diabetes has also been uncovered. The findings open a window for the development of HCA-based predictive markers as well as anti-diabetic drugs. The research results have been published in the international scientific journals Cell Metabolism and ....
Diet and lifestyle may play a significant role in Alzheimer s disease For years, research to pin down the underlying cause of Alzheimer s Disease has been focused on plaque found to be building up in the brain in AD patients. But treatments targeted at breaking down that buildup have been ineffective in restoring cognitive function, suggesting that the buildup may be a side effect of AD and not the cause itself. A new study led by a team of Brigham Young University researchers finds novel cellular-level support for an alternate theory that is growing in strength: Alzheimer s could actually be a result of metabolic dysfunction in the brain. In other words, there is growing evidence that diet and lifestyle are at the heart of Alzheimer s Disease. ....
(0) - Global self-injection device market to Clock CAGR of 13.4% during 2018 - 2026, versatile use of pen injectors for management of chronic disorders - Technological advancements in wearable injectors and auto injectors to benefit home care, both expected to be lucrative segments ALBANY, N.Y., April 1, 2021 /PRNewswire/ Self-injection devices have become a mainstay of numerous infusion therapies for long-term management of chronic conditions, mainly by making subcutaneous delivery of medicines and hormones easier. This is the key drive for the evolution in the self injection devices market. Advances in design and engineering of self-injection devices are reinforcing uptake in patient populations in homecare settings, notably for rheumatoid arthritis and diabetes. A number of choices among target patients in the use of these self-injection devices in chronic inflammatory diseases are propelling strides in the market. Among various technologies, pen injecto ....
Amino acids signaling controls whole-body glucose homeostasis, study shows Amino acids are a major nutrient type for humans and are used as building blocks and a source of energy for cells. Amino acids have also recently been recognized as chemical signals that control cell growth and metabolism. Researchers from Rutgers Cancer Institute of New Jersey previously identified a small protein called Rab1A that regulates amino acid signaling. In a recent study, researchers explored the physiological role of Rab1A in mammals using mice though a technique in which one of an organism s genes is made inoperative, known as genetic knockout. Steven Zheng, PhD, chief of Cancer Pharmacology and researcher at Rutgers Cancer Institute is senior author of the work and shares more about the findings published in the March 16 online edition of ....