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Gattefossé x BioMeca Develop 3D Dermal Microtissue to Study Elasticity


Gattefossé x BioMeca Develop 3D Dermal Microtissue to Study Elasticity
March 16, 2021
Contact Author Michele Behrens
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Gattefossé and BioMeca jointly developed a model of 3D dermal microtissue to study elastic properties in vitro.
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3D, spheroid-based, scaffold-free microtissues were created by Gattefossé to mimic and study the intrinsic elastic properties of the dermis in vitro. BioMeca then leveraged its expertise to analyze the substrates, the dynamics therein and potential actives of interest.
According to Gattefossé, during aging, human skin undergoes alterations of its biomechanical properties; particularly, a loss of elasticity that results in skin sagging. Dermal elastic fibers represent the primary components that support tissue compliance and resilience but as time goes by, their organization and functionality decline, which makes them a preferred target for cosmetic anti-aging strategies. ....

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HistoIndex and Consortium Partners Awarded S$1.2M for the Development of AI-based Diagnostics Tool in the Identification of High-Risk Nonalcoholic Fatty Liver Disease Population


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HistoIndex joins forces with a consortium of partners from NHS Health Boards, UK universities and technology companies for the development of a novel AI-based integrated diagnostic tool.
There is currently no available method to accurately identify patients with NAFLD who are at a higher risk of developing a more progressive form of liver disease (non-alcoholic steatohepatitis or NASH) that can lead to cirrhosis, liver cancer and premature death. NASH is an unmet liver condition that awaits an FDA-approved treatment.
Having an AI-based diagnostics tool that provides a fully quantitative and accurate assessment of fibrosis will provide clinicians with a deeper understanding of the disease and its progressive features, which will aid in enrolling high-risk patients for NASH clinical trials. ....

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